Gene Symbol | FUT6 |
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Entrez Gene | 2528 |
Alt Symbol | FCT3A, FT1A, Fuc-TVI, FucT-VI |
Species | Human |
Gene Type | protein-coding |
Description | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
Other Description | alpha-(1,3)-fucosyltransferase 6|fucosyltransferase VI|galactoside 3-L-fucosyltransferase |
Swissprots | P51993 Q9UND8 D6W637 A6NEX0 |
Accessions | AAB03078 EAW69136 EAW69137 EAW69138 EAW69139 P51993 AF131211 AAD33509 AK098073 AK225795 AK313130 BAG35950 BC040472 BC061700 AAH61700 DA426469 DA622182 DA628976 M98825 AAA99222 U27331 AAC50190 U27332 AAC50191 U27333 AAC50192 U27334 AAC50193 U27335 AAC50194 U27336 AAC50195 U27337 AAC50196 XM_005259526 XP_005259583 XM_005259527 XP_005259584 XM_011527868 XP_011526170 XM_011527869 XP_011526171 XM_011527870 XP_011526172 XM_011527871 XP_011526173 XM_011527872 XP_011526174 XM_011527873 XP_011526175 XM_011527874 XP_011526176 XM_011527875 XP_011526177 XM_011527876 XP_011526178 XM_011527877 XP_011526179 XM_011527878 XP_011526180 XM_011527879 XP_011526181 NM_000150 NP_000141 NM_001040701 NP_001035791 |
Function | Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates. |
Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. |
Tissue Specificity | Kidney, liver, colon, small intestine, bladder, uterus and salivary gland. |
Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |
FucT-VI CRISPR/Cas9 KO Plasmid (h) - sc-409615 from Santa Cruz Biotechnology
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FucT-VI HDR Plasmid (h) - sc-409615-HDR from Santa Cruz Biotechnology
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FucT-VI Double Nickase Plasmid (h) - sc-409615-NIC from Santa Cruz Biotechnology
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FucT-VI Double Nickase Plasmid (h2) - sc-409615-NIC-2 from Santa Cruz Biotechnology
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FucT-VI CRISPR Activation Plasmid (h) - sc-409615-ACT from Santa Cruz Biotechnology
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FucT-VI CRISPR Activation Plasmid (h2) - sc-409615-ACT-2 from Santa Cruz Biotechnology
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FucT-VI Lentiviral Activation Particles (h) - sc-409615-LAC from Santa Cruz Biotechnology
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FucT-VI Lentiviral Activation Particles (h2) - sc-409615-LAC-2 from Santa Cruz Biotechnology
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FucT-VI siRNA (h) - sc-40587 from Santa Cruz Biotechnology
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FucT-VI shRNA Plasmid (h) - sc-40587-SH from Santa Cruz Biotechnology
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FucT-VI shRNA (h) Lentiviral Particles - sc-40587-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU046631 from Sigma-Aldrich
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MISSION® esiRNA - EHU135541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9002 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9002 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07271 from Sigma-Aldrich
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FUT6 siRNA (Human) - CRH1673 from Cohesion Biosciences
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FUT6 - MBS8233581 from MyBioSource
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shRNA set against Human FUT6(NM_000150.2) - SHH070733 from Creative biogene
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Human FUT6 siRNA - orb262175 from Biorbyt
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FUT6 shRNA Plasmid (Human) - CHH1673 from Cohesion Biosciences
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FUT6 miRNA 3'UTR clone - MiUTR1H-03882 from Creative biogene
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