Gene Symbol | PLA2G5 |
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Entrez Gene | 5322 |
Alt Symbol | FRFB, GV-PLA2, PLA2-10, hVPLA(2) |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group V |
Other Description | Ca2+-dependent phospholipase A2|calcium-dependent phospholipase A2|phosphatidylcholine 2-acylhydrolase 5 |
Swissprots | Q8N435 P39877 |
Accessions | AAR92480 EAW94911 EAW94912 EAW94913 P39877 AK097693 BAG53516 AV709457 BC036792 AAH36792 BM684907 BM705479 BX648966 U03090 AAC28886 XM_005245891 XP_005245948 XM_005245892 XP_005245949 XM_005245893 XP_005245950 XM_006710696 XP_006710759 XM_011541584 XP_011539886 XM_011541585 XP_011539887 XM_011541586 XP_011539888 XM_011541587 XP_011539889 XM_011541588 XP_011539890 XM_011541589 XP_011539891 XM_011541590 XP_011539892 XM_011541591 XP_011539893 XM_011541592 XP_011539894 NM_000929 NP_000920 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L- alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L- alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle. |
Subcellular Location | Secreted. |
Tissue Specificity | Heart, placenta and less abundantly, in lung. Detected in the outer and inner plexiform layers of the retina (at protein level). {ECO:0000269|PubMed:22137173}. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
Human Secretory phospholipase A2 Type V full length protein - ab63846 from Abcam
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PLA2G5 Antibody Blocking Peptide - LS-E3566 from LifeSpan Bioscience
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PLA2G5 Antibody Blocking Peptide - LS-E15242 from LifeSpan Bioscience
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PLA2G5 Antibody Blocking Peptide - LS-E15241 from LifeSpan Bioscience
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Recombinant Human Secretory phospholipase A2 Type V Protein - H00005322-P01 from Novus Biologicals
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PLA2G5-Antibody-C-term-Blocking-Peptide - BP14763b from Abgent, a WuXi AppTec company
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PLA2G5 Protein (OPPA00847) - OPPA00847 from Aviva Systems Biology
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Human PLA2G5 protein - orb90228 from Biorbyt
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PLA2G5 Blocking Peptide - 33R-10222 from Fitzgerald
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PLA2G5 Blocking Peptide - 33R-6140 from Fitzgerald
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PLA2G5 - H00005322-P01-10 from Acris Antibodies
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PLA2G5 - H00005322-P01-25 from Acris Antibodies
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Secreted Phospholipase A2-V, Human Recombinant - 228-11271-1 from RayBiotech
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Recombinant Human PLA2G5 - 228-11271-2 from RayBiotech
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Recombinant Human PLA2G5 - 228-11271-3 from RayBiotech
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PLA2G5 Human - ENPS-335 from NeoScientific
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Recombinant Human Secreted Phospholipase A2-V - BP000896-ENZ-328 from Syd Labs
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Recombinant Human Phospholipase A2, Group V, His-tagged - PLA2G5-71H from Creative Biomart
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Recombinant Human PLA2G5, His-tagged - PLA2G5-31349TH from Creative Biomart
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PLA2G5 Human - JNV-734 from Reagent Proteins
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Recombinant Phospholipase A2, Group V (PLA2G5) - RPD832Hu01 from Uscn Life Science Inc.
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Recombinant Phospholipase A2, Group V (PLA2G5) - RPD832Hu01 from Cloud-clone
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Recombinant Human Calcium-dependent phospholipase A2(PLA2G5) - CSB-YP018103HU CSB-EP018103HU CSB-BP018103HU CSB-MP018103HU from Cusabio
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Calcium-dependent phospholipase A2, Recombinant Protein - MBS952738 from MyBioSource
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Recombinant Human Phospholipase A2 Group V His - CSI12705 from Cell Science
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