Gene Symbol | FXR1 |
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Entrez Gene | 8087 |
Alt Symbol | FXR1P |
Species | Human |
Gene Type | protein-coding |
Description | fragile X mental retardation, autosomal homolog 1 |
Other Description | fragile X mental retardation syndrome-related protein 1|hFXR1p |
Swissprots | Q7Z450 P51114 A8K9B8 Q8N6R8 |
Accessions | CAH05519 CAH05520 EAW78365 EAW78366 EAW78367 EAW78368 EAW78369 EAW78370 EAW78371 EAW78372 P51114 AF075028 AK225334 AK292633 BAF85322 AK294603 BAG57790 AK297254 BAG59733 AK297331 BAG59790 AK302197 BAG63558 AM393057 CAL37935 AM393164 CAL38042 AM393496 CAL38373 AU280585 AY341428 AAQ20045 BC010382 BC028983 AAH28983 BQ016986 BX956500 DC352767 U25165 AAC50155 X90874 CAA62382 XM_005247813 XP_005247870 XM_005247814 XP_005247871 XM_005247815 XP_005247872 XM_005247816 XP_005247873 XM_006713775 XP_006713838 XM_011513215 XP_011511517 XM_011513216 XP_011511518 XM_011513217 XP_011511519 NM_001013438 NP_001013456 NM_005087 NP_005078 NM_001013439 NP_001013457 |
Function | RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:7781595}. |
Tissue Specificity | Expressed in all tissues examined including heart, brain, kidney and testis. {ECO:0000269|PubMed:7781595}. |
Top Pathways | RNA transport |
FXR1 CRISPR/Cas9 KO Plasmid (h) - sc-402570 from Santa Cruz Biotechnology
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FXR1 HDR Plasmid (h) - sc-402570-HDR from Santa Cruz Biotechnology
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FXR1 Double Nickase Plasmid (h) - sc-402570-NIC from Santa Cruz Biotechnology
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FXR1 Double Nickase Plasmid (h2) - sc-402570-NIC-2 from Santa Cruz Biotechnology
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FXR1 CRISPR Activation Plasmid (h) - sc-402570-ACT from Santa Cruz Biotechnology
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FXR1 CRISPR Activation Plasmid (h2) - sc-402570-ACT-2 from Santa Cruz Biotechnology
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FXR1 Lentiviral Activation Particles (h) - sc-402570-LAC from Santa Cruz Biotechnology
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FXR1 Lentiviral Activation Particles (h2) - sc-402570-LAC-2 from Santa Cruz Biotechnology
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FXR1 siRNA (h) - sc-35423 from Santa Cruz Biotechnology
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FXR1 shRNA Plasmid (h) - sc-35423-SH from Santa Cruz Biotechnology
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FXR1 shRNA (h) Lentiviral Particles - sc-35423-V from Santa Cruz Biotechnology
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FXR1 RNAi - H00008087-R03 from Novus Biologicals
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FXR1 RNAi - H00008087-R02 from Novus Biologicals
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FXR1 RNAi - H00008087-R01 from Novus Biologicals
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MISSION® esiRNA - EHU080421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9009 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9009 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08298 from Sigma-Aldrich
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FXR1 siRNA (Human) - CRH5364 from Cohesion Biosciences
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FXR1 - MBS8212581 from MyBioSource
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shRNA set against Human FXR1 (NM_001013439.2) - SHH297897 from Creative biogene
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Human FXR1 siRNA - orb265866 from Biorbyt
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FXR1 shRNA Plasmid (Human) - CHH5364 from Cohesion Biosciences
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FXR1 miRNA 3'UTR clone - MiUTR3H-03650 from Creative biogene
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FXR1 miRNA 3'UTR clone - MiUTR3H-03651 from Creative biogene
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