| Gene Symbol |
BCAP31
|
| Entrez Gene |
10134
|
| Alt Symbol |
6C6-AG, BAP31, CDM, DDCH, DXS1357E
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
B-cell receptor-associated protein 31
|
| Other Description |
6C6-AG tumor-associated antigen|BCR-associated protein Bap31|p28 Bap31
|
| Swissprots |
Q13836 B3KQ79 D3DWV5 Q96CF0 P51572
|
| Accessions |
AAA79508 EAW72818 EAW72819 EAW72820 EAW72821 EAW72822 EAW72823 EAW72824 EAW72825 P51572 AI123868 AK057613 BAG51941 AK125631 BAG54226 AK222494 BAD96214 AK223059 BAD96779 AM392839 CAL37717 AU132745 BC014323 AAH14323 BC065292 AAH65292 BE729820 BG779815 BX474419 CX164660 DA134013 DA819112 X81109 CAA57015 Z31696 CAA83501 NM_001139441 NP_001132913 NM_001139457 NP_001132929 NM_001256447 NP_001243376 NM_005745 NP_005736
|
| Function |
Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8- mediated apoptosis. {ECO:0000269|PubMed:10958671, ECO:0000269|PubMed:18287538, ECO:0000269|PubMed:9396746}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complex.
|
| Tissue Specificity |
Ubiquitous. Highly expressed in neurons and discrete endocrine cells. {ECO:0000269|PubMed:11561007}.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|