ABCC9
| Gene Symbol | ABCC9 |
|---|---|
| Entrez Gene | 10060 |
| Alt Symbol | ABC37, ATFB12, CANTU, CMD1O, SUR2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| Other Description | ATP-binding cassette sub-family C member 9|ATP-binding cassette transporter sub-family C member 9|sulfonylurea receptor 2 |
| Swissprots | O60707 O60706 |
| Accessions | AAC16057 AAC16058 EAW96452 EAW96453 EAW96454 EAW96455 EAW96456 EAW96457 EAW96458 EAW96459 EAW96460 O60706 AK056519 AK092535 AK094171 BAC04300 BC033804 AAH33804 BX537513 BX640893 CA389699 XM_005253284 XP_005253341 XM_005253286 XP_005253343 XM_005253287 XP_005253344 XM_005253288 XP_005253345 XM_005253289 XP_005253346 XM_005253290 XP_005253347 XM_006719025 XP_006719088 XM_011520545 XP_011518847 NM_005691 NP_005682 NM_020297 NP_064693 NM_020298 |
| Function | Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. {ECO:0000269|PubMed:9831708}. |
| Subcellular Location | Membrane {ECO:0000255|PROSITE- ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}. |
| Top Pathways | ABC transporters |
SUR-2 CRISPR/Cas9 KO Plasmid (h) - sc-401399 from Santa Cruz Biotechnology
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SUR-2 HDR Plasmid (h) - sc-401399-HDR from Santa Cruz Biotechnology
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SUR-2 Double Nickase Plasmid (h) - sc-401399-NIC from Santa Cruz Biotechnology
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SUR-2 Double Nickase Plasmid (h2) - sc-401399-NIC-2 from Santa Cruz Biotechnology
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SUR-2 CRISPR Activation Plasmid (h) - sc-401399-ACT from Santa Cruz Biotechnology
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SUR-2 CRISPR Activation Plasmid (h2) - sc-401399-ACT-2 from Santa Cruz Biotechnology
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SUR-2 Lentiviral Activation Particles (h) - sc-401399-LAC from Santa Cruz Biotechnology
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SUR-2 Lentiviral Activation Particles (h2) - sc-401399-LAC-2 from Santa Cruz Biotechnology
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SUR-2 siRNA (h) - sc-42636 from Santa Cruz Biotechnology
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SUR-2 shRNA Plasmid (h) - sc-42636-SH from Santa Cruz Biotechnology
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SUR-2 shRNA (h) Lentiviral Particles - sc-42636-V from Santa Cruz Biotechnology
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SUR-2B siRNA (h) - sc-44132 from Santa Cruz Biotechnology
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SUR-2B shRNA Plasmid (h) - sc-44132-SH from Santa Cruz Biotechnology
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SUR-2B shRNA (h) Lentiviral Particles - sc-44132-V from Santa Cruz Biotechnology
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ABCC9 RNAi - H00010060-R04 from Novus Biologicals
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ABCC9 RNAi - H00010060-R06 from Novus Biologicals
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MISSION® esiRNA - EHU088351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2452 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2452 from Sigma-Aldrich
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ABCC9 siRNA (Human) - CRH6776 from Cohesion Biosciences
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ABCC9 RNAi - H00010060-R05 from Novus Biologicals
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ABCC9 - MBS8208001 from MyBioSource
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shRNA set against Human ABCC9 (NM_005691.2) - SHH229186 from Creative biogene
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shRNA set against Human ABCC9(NM_005691.2) - SHG024409 from Creative biogene
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shRNA set against Human ABCC9(NM_020297.2) - SHG024559 from Creative biogene
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