| Gene Symbol |
Stat5b
|
| Entrez Gene |
20851
|
| Alt Symbol |
-
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
signal transducer and activator of transcription 5B
|
| Other Description |
mammary gland factor STAT5B
|
| Swissprots |
Q9R0X8 Q8K3Q1 Q60804 A2A5D5 Q541Q5 P42232 Q9JKM1
|
| Accessions |
AAF62911 CAB51862 CAG32956 P42232 AI414876 AK004071 BAB23152 AK009277 AK045531 AK088966 AK137889 AK150098 BAE29305 AK154014 BAE32317 AK154664 BAE32752 AK190610 AK191910 AY040231 AAK74074 AY042906 AAL05590 AY044901 AAK97791 AY044902 AAK97792 AY044903 AAK97793 BC024319 AAH24319 U21110 AAC52282 Z48539 CAA88420 XM_006532723 XP_006532786 NM_001113563 NP_001107035 NM_011489 NP_035619
|
| Function |
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. {ECO:0000269|PubMed:11773439}.
|
| Subcellular Location |
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
|
| Tissue Specificity |
In the virgin, found in most tissues. Particularly abundant in muscle tissue of virgin and lactating females, and of males.
|
| Top Pathways |
Chemokine signaling pathway, Prolactin signaling pathway, Viral carcinogenesis, Measles, HTLV-I infection
|