| Gene Symbol |
lias
|
| Entrez Gene |
443960
|
| Alt Symbol |
LS, Lip-syn
|
| Species |
Xenopus
|
| Gene Type |
protein-coding
|
| Description |
lipoic acid synthetase
|
| Other Description |
LS|lip-syn|lipoate synthase|lipoic acid synthase|lipoyl synthase, mitochondrial
|
| Swissprots |
Q6GQ48
|
| Accessions |
CBN72481 Q6GQ48 BC072900 AAH72900 NM_001092065 NP_001085534
|
| Function |
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}.
|
| Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}.
|
| Top Pathways |
Lipoic acid metabolism
|