Gene Symbol |
Cyp4a2
|
Entrez Gene |
24306
|
Alt Symbol |
Cyp4a11
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
cytochrome P450, family 4, subfamily a, polypeptide 2
|
Other Description |
CYPIVA2|P-450 IV4AII|P-450 K-2|P450 K-5|P450-LA-omega 2|cytochrome P-450 K-2|cytochrome P450 4A2|cytochrome P450 K-5|cytochrome P450, subfamily 4A, polypeptide 11|cytochrome P450, subfamily IVA, polypeptide 11|cytochrome P450-LA-omega 2|lauric acid omega-hydroxylase
|
Swissprots |
P20816 Q4G071
|
Accessions |
AAA41039 P20816 BC078684 AAH78684 BC098705 AAH98705 NM_001044770 NP_001038235
|
Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
Top Pathways |
PPAR signaling pathway, Vascular smooth muscle contraction, Inflammatory mediator regulation of TRP channels, Arachidonic acid metabolism, Fatty acid degradation
|