Cyp4a2

Gene Symbol Cyp4a2
Entrez Gene 24306
Alt Symbol Cyp4a11
Species Rat
Gene Type protein-coding
Description cytochrome P450, family 4, subfamily a, polypeptide 2
Other Description CYPIVA2|P-450 IV4AII|P-450 K-2|P450 K-5|P450-LA-omega 2|cytochrome P-450 K-2|cytochrome P450 4A2|cytochrome P450 K-5|cytochrome P450, subfamily 4A, polypeptide 11|cytochrome P450, subfamily IVA, polypeptide 11|cytochrome P450-LA-omega 2|lauric acid omega-hydroxylase
Swissprots P20816 Q4G071
Accessions AAA41039 P20816 BC078684 AAH78684 BC098705 AAH98705 NM_001044770 NP_001038235
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Top Pathways PPAR signaling pathway, Vascular smooth muscle contraction, Inflammatory mediator regulation of TRP channels, Arachidonic acid metabolism, Fatty acid degradation