ARID1B

Gene Symbol ARID1B
Entrez Gene 57492
Alt Symbol 6A3-5, BAF250B, BRIGHT, DAN15, ELD/OSA1, MRD12, OSA2, P250R
Species Human
Gene Type protein-coding
Description AT rich interactive domain 1B (SWI1-like)
Other Description ARID domain-containing protein 1B|AT-rich interactive domain-containing protein 1B|BRG1-associated factor 250b|BRG1-binding protein ELD/OSA1|ELD (eyelid)/OSA protein
Swissprots Q5VYC4 Q8IZY8 Q8TEV0 Q5JRD1 Q8NFD5 Q9ULI5 Q99491 Q8TF02
Accessions CCQ43553 EAW47678 EAW47679 EAW47680 EAW47681 EAW47682 EAW47683 EAW47684 EAW47685 Q8NFD5 AB033061 BAA86549 AF253515 AAN70985 AF259792 AAG36928 AF468300 AAL76077 AF521671 AAN03447 AK000921 BAA91426 AK025945 AK074180 BAB85006 AK302356 BAG63682 BC009543 BU733862 CB240584 Y08266 CAA69592 XM_005267069 XP_005267126 XM_011535984 XP_011534286 XM_011535985 XP_011534287 XM_011535986 XP_011534288 XM_011535987 XP_011534289 XM_011535988 XP_011534290 NM_017519 NP_059989 NM_020732 NP_065783
Function Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neur
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00355, ECO:0000269|PubMed:11988099}.
Tissue Specificity Widely expressed with high levels in heart, skeletal muscle and kidney. {ECO:0000269|PubMed:11988099, ECO:0000269|PubMed:12200431, ECO:0000269|PubMed:12665591}.

ARID1B CRISPR/Cas9 KO Plasmid (h) - sc-402365 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B HDR Plasmid (h) - sc-402365-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B Double Nickase Plasmid (h) - sc-402365-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B Double Nickase Plasmid (h2) - sc-402365-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B CRISPR Activation Plasmid (h) - sc-402365-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B CRISPR Activation Plasmid (h2) - sc-402365-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B Lentiviral Activation Particles (h) - sc-402365-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B Lentiviral Activation Particles (h2) - sc-402365-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ARID1B siRNA (h) - sc-43571 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ARID1B shRNA Plasmid (h) - sc-43571-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ARID1B shRNA (h) Lentiviral Particles - sc-43571-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ARID1B RNAi - H00057492-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ARID1B RNAi - H00057492-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

ARID1B RNAi - H00057492-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU127901 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU141841 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN3466 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3466 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ARID1B siRNA (Human) - CRJ1481 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ARID1B - MBS8230188 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ARID1B (NM_017519.2) - SHH239938 from Creative biogene

Category siRNA
Species Reactivities Human

ARID1B shRNA Plasmid (Human) - CHJ1481 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ARID1B miRNA 3'UTR clone - MiUTR3H-13304 from Creative biogene

Species Reactivities Human

ARID1B miRNA 3'UTR clone - MiUTR3H-13305 from Creative biogene

Species Reactivities Human
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