| Gene Symbol |
TAPBP
|
| Entrez Gene |
6892
|
| Alt Symbol |
NGS17, TAPA, TPN, TPSN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TAP binding protein (tapasin)
|
| Other Description |
NGS-17|TAP-associated protein|TAP-binding protein|tapasin
|
| Swissprots |
Q9HAN8 Q9Y6K2 Q9UEE0 O15210 Q5STJ8 E9PGM2 Q96KK7 A2AB91 Q9UIZ6 Q5STK6 B2ZUA4 O15272 O15533 B0V0A6 A2ABC0 Q5STQ6 Q9UEE4 B0V003 Q5STQ5 Q66K65
|
| Accessions |
BAA28758 BAA28759 EAX03715 EAX03716 EAX03717 EAX03718 EAX03719 EAX03720 O15533 AB010639 BAA28757 AF009510 AAC20076 AF029750 AAB82949 AF067286 AAD32924 AF314222 AAG33061 AU117273 AW028178 AW451052 AY007154 BC064966 AAH64966 BC080574 AAH80574 BI523615 EU693375 ACD68200 HQ447577 ADQ32063 Y13582 CAA73909 XM_011514828 XP_011513130 XM_011547276 XP_011545578 XM_011547679 XP_011545981 XM_011548077 XP_011546379 XM_011548266 XP_011546568 NM_003190 NP_003181 NM_172208 NP_757345 NM_172209 NP_757346
|
| Function |
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). {ECO:0000269|PubMed:10636848}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Neutrophils, mostly in fully differentiated cells.
|
| Top Pathways |
Antigen processing and presentation
|