Gene Symbol | SOD2 |
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Entrez Gene | 6648 |
Alt Symbol | IPOB, MNSOD, MVCD6 |
Species | Human |
Gene Type | protein-coding |
Description | superoxide dismutase 2, mitochondrial |
Other Description | Mn superoxide dismutase|indophenoloxidase B|manganese-containing superoxide dismutase|mangano-superoxide dismutase|superoxide dismutase [Mn], mitochondrial |
Swissprots | Q96EE6 P78434 B3KUK2 B2R7R1 B4DL20 P04179 Q16792 E1P5A9 Q9P2Z3 B4E3K9 Q5TCM1 |
Accessions | AAA83933 AAC15835 AAD14248 AAP03428 BAA18955 EAW47629 EAW47630 EAW47631 P04179 AK296809 BAG59382 AK304766 BAG65521 AK313082 BAG35908 AL050388 CAB62521 AL691784 AM392836 CAL37714 AY280718 AAP34407 AY280719 AAP34408 AY280720 AAP34409 AY280721 AAP34410 BC001980 BC012423 AAH12423 BC016015 BC016934 AAH16934 BC035422 BC041951 BG699596 BM994509 BT006967 AAP35613 BU164685 BU741675 DQ003134 AAY21807 DQ890587 ABM92204 DQ893752 ABM84678 M36693 AAA36622 X07834 CAA30687 X14322 CAA32502 X15132 CAA33228 X59445 CAA42066 Y00472 CAA68533 Y00985 CAA68791 NM_000636 NP_000627 NM_001024465 NP_001019636 NM_001024466 NP_001019637 |
Function | Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. {ECO:0000269|PubMed:10334867}. |
Subcellular Location | Mitochondrion matrix. |
Top Pathways | Huntington's disease, Peroxisome |
SOD-2 CRISPR/Cas9 KO Plasmid (h) - sc-400230 from Santa Cruz Biotechnology
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SOD-2 HDR Plasmid (h) - sc-400230-HDR from Santa Cruz Biotechnology
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SOD-2 Double Nickase Plasmid (h) - sc-400230-NIC from Santa Cruz Biotechnology
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SOD-2 Double Nickase Plasmid (h2) - sc-400230-NIC-2 from Santa Cruz Biotechnology
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SOD-2 CRISPR Activation Plasmid (h) - sc-400230-ACT from Santa Cruz Biotechnology
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SOD-2 CRISPR Activation Plasmid (h2) - sc-400230-ACT-2 from Santa Cruz Biotechnology
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SOD-2 Lentiviral Activation Particles (h) - sc-400230-LAC from Santa Cruz Biotechnology
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SOD-2 Lentiviral Activation Particles (h2) - sc-400230-LAC-2 from Santa Cruz Biotechnology
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SOD-2 siRNA (h) - sc-41655 from Santa Cruz Biotechnology
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SOD-2 shRNA Plasmid (h) - sc-41655-SH from Santa Cruz Biotechnology
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SOD-2 shRNA (h) Lentiviral Particles - sc-41655-V from Santa Cruz Biotechnology
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SOD2/Mn-SOD RNAi - H00006648-R03 from Novus Biologicals
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MISSION® esiRNA - EHU075891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20327 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20327 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07278 from Sigma-Aldrich
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SOD2 siRNA (Human) - CRH4528 from Cohesion Biosciences
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SOD2/Mn-SOD RNAi - H00006648-R02 from Novus Biologicals
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SOD2/Mn-SOD RNAi - H00006648-R01 from Novus Biologicals
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SOD2 - MBS8206711 from MyBioSource
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shRNA set against Human SOD2 (NM_000636.2) - SHH415032 from Creative biogene
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shRNA set against Human SOD2(NM_000636.2) - SHL024564 from Creative biogene
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shRNA set against Human SOD2(NM_001024466.1) - SHL024618 from Creative biogene
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Human SOD2 siRNA - orb265030 from Biorbyt
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SOD2 shRNA Plasmid (Human) - CHH4528 from Cohesion Biosciences
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