Gene Symbol | P4HA1 |
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Entrez Gene | 5033 |
Alt Symbol | P4HA |
Species | Human |
Gene Type | protein-coding |
Description | prolyl 4-hydroxylase, alpha polypeptide I |
Other Description | C-P4Halpha(I)|collagen prolyl 4-hydroxylase alpha(I)|procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I|procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1|prolyl 4-hydroxylase subunit alpha-1 |
Swissprots | P13674 C9JL12 Q5VSQ5 Q15082 Q15083 |
Accessions | AAA59068 AAA59069 CDM55387 CDM55568 EAW54467 EAW54468 EAW54469 EAW54470 P13674 AA780802 AI061083 AK222960 BAD96680 AK312593 AL702003 BC034998 AAH34998 CD013929 CD013930 DB030709 DQ891669 ABM82595 DQ894855 ABM85781 M24486 AAA36534 M24487 AAA36535 NM_000917 NP_000908 NM_001017962 NP_001017962 NM_001142595 NP_001136067 NM_001142596 NP_001136068 |
Function | Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. |
Subcellular Location | Endoplasmic reticulum lumen. |
Top Pathways | Arginine and proline metabolism |
P4HA1 CRISPR/Cas9 KO Plasmid (h) - sc-407173 from Santa Cruz Biotechnology
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P4HA1 HDR Plasmid (h) - sc-407173-HDR from Santa Cruz Biotechnology
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P4HA1 Double Nickase Plasmid (h) - sc-407173-NIC from Santa Cruz Biotechnology
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P4HA1 Double Nickase Plasmid (h2) - sc-407173-NIC-2 from Santa Cruz Biotechnology
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P4HA1 CRISPR Activation Plasmid (h) - sc-407173-ACT from Santa Cruz Biotechnology
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P4HA1 CRISPR Activation Plasmid (h2) - sc-407173-ACT-2 from Santa Cruz Biotechnology
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P4HA1 Lentiviral Activation Particles (h) - sc-407173-LAC from Santa Cruz Biotechnology
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P4HA1 Lentiviral Activation Particles (h2) - sc-407173-LAC-2 from Santa Cruz Biotechnology
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P4HA1 siRNA (h) - sc-90782 from Santa Cruz Biotechnology
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P4HA1 shRNA Plasmid (h) - sc-90782-SH from Santa Cruz Biotechnology
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P4HA1 shRNA (h) Lentiviral Particles - sc-90782-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU081741 from Sigma-Aldrich
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MISSION® esiRNA - EHU043381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16238 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16238 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07525 from Sigma-Aldrich
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P4HA1 siRNA (Human) - CRH3346 from Cohesion Biosciences
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shRNA set against Human P4HA1 (NM_000917.3) - SHH369640 from Creative biogene
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Human P4HA1 siRNA - orb263848 from Biorbyt
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P4HA1 shRNA Plasmid (Human) - CHH3346 from Cohesion Biosciences
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P4HA1 miRNA 3'UTR clone - MiUTR3H-01833 from Creative biogene
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P4HA1 miRNA 3'UTR clone - MiUTR3H-01834 from Creative biogene
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P4HA1 miRNA 3'UTR clone - MiUTR3H-01835 from Creative biogene
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P4HA1 miRNA 3'UTR clone - MiUTR3H-01836 from Creative biogene
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