| Gene Symbol |
THSD4
|
| Entrez Gene |
79875
|
| Alt Symbol |
ADAMTSL-6, ADAMTSL6, FVSY9334, PRO34005
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thrombospondin, type I, domain containing 4
|
| Other Description |
A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6|ADAMTS-like protein 6|thrombospondin type-1 domain-containing protein 4
|
| Swissprots |
Q6MZI3 B2RTY3 B4DR13 Q6ZMP0 Q6UXZ8 Q9H8E4
|
| Accessions |
EAW77873 EAW77874 EAW77875 Q6ZMP0 AK000582 AK023772 BAB14673 AK130734 AK131551 BAD18685 AK299056 BAG61125 AK303870 BAG64808 AL049464 AY358143 AAQ88510 BC008840 BC140868 AAI40869 BX641106 CAE46049 BX648716 BX648747 XM_006720692 XP_006720755 XM_011522043 XP_011520345 XM_011522044 XP_011520346 XM_011522045 XP_011520347 NM_001286429 NP_001273358 NM_024817 NP_079093
|
| Function |
Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|
![Western Blot: THSD4 Antibody [NBP1-89243] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue<br/>Lane 6: Human tonsil tissue](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_3/25599_THSD4-Antibody-Western-Blot-NBP1-89243-img0005.jpg)
