Gene Symbol | Inhba |
---|---|
Entrez Gene | 29200 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | inhibin beta-A |
Other Description | activin A|activin beta-A chain|inhibin beta A chain |
Swissprots | P18331 |
Accessions | EDL87403 P18331 M37482 AAA41436 XM_006254001 XP_006254063 XM_008771712 XP_008769934 XM_008771713 XP_008769935 XM_008771714 XP_008769936 XM_008771715 XP_008769937 XM_008771716 XP_008769938 NM_017128 NP_058824 |
Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |