| Gene Symbol |
ZMIZ1
|
| Entrez Gene |
57178
|
| Alt Symbol |
MIZ, RAI17, TRAFIP10, ZIMP10, hZIMP10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger, MIZ-type containing 1
|
| Other Description |
FLJ00092 protein|RP11-519K18.1|retinoic acid induced 17|zinc finger MIZ domain-containing protein 1|zinc finger-containing, Miz1, PIAS-like protein on chromosome 10
|
| Swissprots |
Q5JSH9 Q7Z7E6 Q9ULJ6
|
| Accessions |
EAW54639 EAW54640 EAW54641 EAW54642 EAW54643 EAW54644 Q9ULJ6 AB033050 BAA86538 AF070622 AF357909 AAQ15173 AK023603 AK024490 BAB15780 AK025812 AK299728 BAG61626 AL049432 AL539520 AY235683 AAP13542 BC007288 AAH07288 BC025342 AAH25342 BC035890 BC049845 BC068072 BC117687 AAI17688 BC172361 AAI72361 BE082814 BX644960 CD657106 CF137779 CF264960 XM_005269987 XP_005270044 XM_005269988 XP_005270045 XM_006717923 XP_006717986 XM_006717924 XP_006717987 XM_006717925 XP_006717988 XM_011539978 XP_011538280 XM_011539979 XP_011538281 XM_011539980 XP_011538282 NM_020338 NP_065071
|
| Function |
Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation.
|
| Subcellular Location |
Nucleus speckle {ECO:0000269|PubMed:14609956}. Cytoplasm {ECO:0000269|PubMed:14609956}.
|
| Tissue Specificity |
Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:14609956}.
|
![Western Blot: Zimp10 Overexpression Lysate (Adult Normal) [NBL1-18044] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Zimp10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7900_Zimp10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-18044-img0002.jpg)