Gene Symbol | STK17A |
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Entrez Gene | 9263 |
Alt Symbol | DRAK1 |
Species | Human |
Gene Type | protein-coding |
Description | serine/threonine kinase 17a |
Other Description | DAP kinase-related apoptosis-inducing protein kinase 1|death-associated protein kinase-related 1|serine/threonine kinase 17a (apoptosis-inducing)|serine/threonine-protein kinase 17A |
Swissprots | A4D1V6 Q9UEE5 Q8IVC8 |
Accessions | AAP22356 AAS02010 EAL24008 EAW94162 EAW94163 EAW94164 Q9UEE5 AB011420 BAA34126 AK097170 BAG53430 AW183478 BC023508 AAH23508 BC047696 AAH47696 BI461892 DQ581570 NM_004760 NP_004751 |
Function | Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species. {ECO:0000269|PubMed:21489989, ECO:0000269|PubMed:9786912}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9786912}. |
Tissue Specificity | Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9786912}. |
DRAK1 CRISPR/Cas9 KO Plasmid (h) - sc-411260 from Santa Cruz Biotechnology
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DRAK1 HDR Plasmid (h) - sc-411260-HDR from Santa Cruz Biotechnology
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DRAK1 Double Nickase Plasmid (h) - sc-411260-NIC from Santa Cruz Biotechnology
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DRAK1 Double Nickase Plasmid (h2) - sc-411260-NIC-2 from Santa Cruz Biotechnology
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DRAK1 CRISPR Activation Plasmid (h) - sc-411260-ACT from Santa Cruz Biotechnology
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DRAK1 CRISPR Activation Plasmid (h2) - sc-411260-ACT-2 from Santa Cruz Biotechnology
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DRAK1 Lentiviral Activation Particles (h) - sc-411260-LAC from Santa Cruz Biotechnology
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DRAK1 Lentiviral Activation Particles (h2) - sc-411260-LAC-2 from Santa Cruz Biotechnology
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DRAK1 siRNA (h) - sc-38980 from Santa Cruz Biotechnology
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DRAK1 shRNA Plasmid (h)-SH - sc-38980-SH from Santa Cruz Biotechnology
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DRAK1 shRNA (h) Lentiviral Particles - sc-38980-V from Santa Cruz Biotechnology
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DRAK1 RNAi - H00009263-R01V from Novus Biologicals
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DRAK1 RNAi - H00009263-R02 from Novus Biologicals
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MISSION® esiRNA - EHU018811 from Sigma-Aldrich
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MISSION® siRNA - SIHK2144 from Sigma-Aldrich
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MISSION® siRNA - SIHK2146 from Sigma-Aldrich
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MISSION® siRNA - SIHK2145 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20731 from Sigma-Aldrich
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STK17A siRNA (Human) - CRH6134 from Cohesion Biosciences
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STK17A - MBS8217414 from MyBioSource
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shRNA set against Human STK17A (NM_004760.2) - SHH419724 from Creative biogene
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Human STK17A siRNA - orb266636 from Biorbyt
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STK17A shRNA Plasmid (Human) - CHH6134 from Cohesion Biosciences
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STK17A miRNA 3'UTR clone - MiUTR1H-10003 from Creative biogene
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