Gene Symbol | SLC25A47 |
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Entrez Gene | 283600 |
Alt Symbol | C14orf68, HDMCP, HMFN1655 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 25, member 47 |
Other Description | HCC-down-regulated mitochondrial carrier protein|hepatocellular carcinoma down-regulated mitochondrial carrier protein|hepatocellular carcinoma-downregulated mitochondrial carrier protein|solute carrier family 25 member 47 |
Swissprots | B2RP39 Q86U14 Q68CL2 Q6PZD8 Q6Q0C1 |
Accessions | EAW81696 EAW81697 EAW81698 EAW81699 Q6Q0C1 AB073385 BAD38636 AK092001 BAG52460 AY569438 AAS80155 AY570298 AAS77211 BC137253 AAI37254 BC137254 AAI37255 BC144549 BX248260 CAD62588 NM_207117 NP_997000 |
Function | Uncoupling protein which may catalyze the physiological 'proton leak' in liver. Overexpression induces the dissipation of mitochondrial membrane potential. {ECO:0000269|PubMed:15322095}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:15322095}; Multi-pass membrane protein {ECO:0000269|PubMed:15322095}. |
Tissue Specificity | Specifically expressed in liver. {ECO:0000269|PubMed:15322095}. |
HDMCP CRISPR/Cas9 KO Plasmid (h) - sc-415327 from Santa Cruz Biotechnology
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HDMCP HDR Plasmid (h) - sc-415327-HDR from Santa Cruz Biotechnology
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HDMCP Double Nickase Plasmid (h) - sc-415327-NIC from Santa Cruz Biotechnology
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HDMCP Double Nickase Plasmid (h2) - sc-415327-NIC-2 from Santa Cruz Biotechnology
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HDMCP CRISPR Activation Plasmid (h) - sc-415327-ACT from Santa Cruz Biotechnology
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HDMCP CRISPR Activation Plasmid (h2) - sc-415327-ACT-2 from Santa Cruz Biotechnology
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HDMCP Lentiviral Activation Particles (h) - sc-415327-LAC from Santa Cruz Biotechnology
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HDMCP Lentiviral Activation Particles (h2) - sc-415327-LAC-2 from Santa Cruz Biotechnology
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HDMCP siRNA (h) - sc-92416 from Santa Cruz Biotechnology
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HDMCP shRNA Plasmid (h) - sc-92416-SH from Santa Cruz Biotechnology
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HDMCP shRNA (h) Lentiviral Particles - sc-92416-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU060271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19516 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19516 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05974 from Sigma-Aldrich
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SLC25A47 siRNA (Human) - CRJ6922 from Cohesion Biosciences
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SLC25A47 - MBS8213300 from MyBioSource
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shRNA set against Human SLC25A47 (NM_207117.2) - SHH409868 from Creative biogene
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Human SLC25A47 siRNA - orb277423 from Biorbyt
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SLC25A47 shRNA Plasmid (Human) - CHJ6922 from Cohesion Biosciences
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SLC25A47 miRNA 3'UTR clone - MiUTR1H-01123 from Creative biogene
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