Gene Symbol | IGF2 |
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Entrez Gene | 3481 |
Alt Symbol | C11orf43, IGF-II, PP9974 |
Species | Human |
Gene Type | protein-coding |
Description | insulin-like growth factor 2 |
Other Description | T3M-11-derived growth factor|insulin-like growth factor 2 (somatomedin A)|insulin-like growth factor II|insulin-like growth factor type 2 |
Swissprots | Q1WM26 Q14299 Q9UC68 Q9UC69 E3UN45 B3KX48 P01344 B7WP08 C9JAF2 P78449 |
Accessions | AAA52536 AAM51825 ACC95538 CAA27155 CAA27156 CAA27157 CAA27249 CAA30717 CAR95138 CAV31678 EAX02485 P01344 AA040827 AF318382 AAL55889 AK025719 AK126688 BAG54360 AK313938 BAG36657 AY971350 AAY40360 BC000531 AAH00531 BC011786 BC042127 BC053318 BC073756 BE270173 BM667567 BP233290 BQ014465 BT007013 AAP35659 CN277570 DA641853 DQ104203 ABD93451 DQ892721 ABM83647 DQ895970 ABM86896 HM481219 ADO21454 HM481220 ADO21455 J03242 AAA52545 M17426 AAA60088 M17863 AAA52443 M29645 AAA52544 S51971 AAD14908 S77035 AAB34155 X00910 CAA25426 X06159 CAA29516 X06160 CAA29517 X06161 CAA29518 X06259 X06260 NM_000612 NP_000603 NM_001007139 NP_001007140 NM_001127598 NP_001121070 NM_001291861 NP_001278790 NM_001291862 NP_001278791 |
Function | The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. |
Subcellular Location | Secreted. |
Top Pathways | Proteoglycans in cancer |
IGF-II CRISPR/Cas9 KO Plasmid (h) - sc-401015 from Santa Cruz Biotechnology
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IGF-II HDR Plasmid (h) - sc-401015-HDR from Santa Cruz Biotechnology
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IGF-II Double Nickase Plasmid (h) - sc-401015-NIC from Santa Cruz Biotechnology
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IGF-II Double Nickase Plasmid (h2) - sc-401015-NIC-2 from Santa Cruz Biotechnology
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IGF-II CRISPR Activation Plasmid (h) - sc-401015-ACT from Santa Cruz Biotechnology
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IGF-II CRISPR Activation Plasmid (h2) - sc-401015-ACT-2 from Santa Cruz Biotechnology
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IGF-II Lentiviral Activation Particles (h) - sc-401015-LAC from Santa Cruz Biotechnology
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IGF-II Lentiviral Activation Particles (h2) - sc-401015-LAC-2 from Santa Cruz Biotechnology
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IGF-II siRNA (h) - sc-39576 from Santa Cruz Biotechnology
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IGF-II shRNA Plasmid (h) - sc-39576-SH from Santa Cruz Biotechnology
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IGF-II shRNA (h) Lentiviral Particles - sc-39576-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU133731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10514 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10514 from Sigma-Aldrich
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IGF2 siRNA (Human) - CRH2352 from Cohesion Biosciences
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IGF2 - MBS8229304 from MyBioSource
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shRNA set against Human IGF2 (NM_000612.4) - SHH317457 from Creative biogene
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Human IGF2 siRNA - orb262854 from Biorbyt
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IGF2 shRNA Plasmid (Human) - CHH2352 from Cohesion Biosciences
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IGF2 miRNA 3'UTR clone - MiUTR4H-TG04437 from Creative biogene
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