OSGEPL1
| Gene Symbol | OSGEPL1 |
|---|---|
| Entrez Gene | 64172 |
| Alt Symbol | Qri7 |
| Species | Human |
| Gene Type | protein-coding |
| Description | O-sialoglycoprotein endopeptidase-like 1 |
| Other Description | N6-L-threonylcarbamoyladenine synthase|O-sialoglycoprotein endopeptidase like 1|O-sialoglycoprotein endopeptidase-like protein 1|probable O-sialoglycoprotein endopeptidase 2|probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial|probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1|putative sialoglycoprotease type 2|t(6)A synthase|t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1|tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1 |
| Swissprots | Q9H4B0 Q96NH5 Q96EV9 |
| Accessions | AAY14771 CBF91713 CBG00264 CBG08622 CBV05233 CBV13784 CBV22144 EAX10890 EAX10891 Q9H4B0 AJ295148 CAC14666 AK055441 BAB70923 AK294841 BAG57948 AK314565 BC011904 AAH11904 DQ893047 ABM83973 DQ896291 ABM87290 XM_005246766 XP_005246823 XM_006712685 XP_006712748 XM_006712686 XP_006712749 XM_011511630 XP_011509932 XM_011511631 XP_011509933 XR_922985 NM_022353 NP_071748 |
| Function | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. {ECO:0000255|HAMAP-Rule:MF_03179}. |
| Subcellular Location | Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03179, ECO:0000269|PubMed:19694617}. |
| Tissue Specificity | Widely expressed, with maximum expression in pituitary gland, prostate, rectum and uterus. {ECO:0000269|PubMed:19694617}. |
OSGEPL1 CRISPR/Cas9 KO Plasmid (h) - sc-418445 from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 HDR Plasmid (h) - sc-418445-HDR from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 Double Nickase Plasmid (h) - sc-418445-NIC from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 Double Nickase Plasmid (h2) - sc-418445-NIC-2 from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 CRISPR Activation Plasmid (h) - sc-418445-ACT from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 CRISPR Activation Plasmid (h2) - sc-418445-ACT-2 from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 Lentiviral Activation Particles (h) - sc-418445-LAC from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 Lentiviral Activation Particles (h2) - sc-418445-LAC-2 from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 siRNA (h) - sc-94989 from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 shRNA Plasmid (h) - sc-94989-SH from Santa Cruz Biotechnology
|
||||||||
OSGEPL1 shRNA (h) Lentiviral Particles - sc-94989-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU055081 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN16170 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16170 from Sigma-Aldrich
|
||||||||
OSGEPL1 siRNA (Human) - CRJ1951 from Cohesion Biosciences
|
||||||||
OSGEPL1 RNAi - H00064172-R01 from Novus Biologicals
|
||||||||
shRNA set against Human OSGEPL1 (NM_022353.2) - SHH368752 from Creative biogene
|
||||||||
shRNA set against Human OSGEPL1(NM_022353.2) - SHR082230 from Creative biogene
|
||||||||
Human OSGEPL1 siRNA - orb272452 from Biorbyt
|
||||||||
OSGEPL1 shRNA Plasmid (Human) - CHJ1951 from Cohesion Biosciences
|
||||||||
OSGEPL1 miRNA 3'UTR clone - MiUTR1H-07403 from Creative biogene
|