| Gene Symbol |
SNAP91
|
| Entrez Gene |
9892
|
| Alt Symbol |
AP180, CALM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptosomal-associated protein, 91kDa
|
| Other Description |
91 kDa synaptosomal-associated protein|assembly protein, 180kDa|clathrin coat assembly protein AP180|clathrin coat-associated protein AP180|phosphoprotein F1-20|synaptosomal-associated protein, 91kDa homolog
|
| Swissprots |
Q5JX13 A8K0L7 Q6P9D3 E5RI02 Q9NTY7 O60641 Q68DL9
|
| Accessions |
EAW48656 EAW48657 EAW48658 EAW48659 EAW48660 EAW48661 O60641 AB014556 BAA31631 AF054993 AAC09352 AK289582 BAF82271 AK294556 BAH11808 AK294898 BAH11918 BC036650 BC044579 BC060818 AAH60818 CR749348 CAH18201 DA110036 DA307867 DA316497 DA323323 DB480068 XM_005248770 XP_005248827 XM_006715615 XP_006715678 XM_011536265 XP_011534567 XM_011536266 XP_011534568 XM_011536267 XP_011534569 XM_011536268 XP_011534570 XM_011536269 XP_011534571 XM_011536270 XP_011534572 XM_011536271 XP_011534573 XM_011536272 XP_011534574 XM_011536273 XP_011534575 XM_011536274 XP_011534576 XM_011536275 XP_011534577 XM_011536276 XP_011534578 XM_011536277 XP_011534579 XM_011536278 XP_011534580 XM_011536279 XP_011534581 XM_011536280 XP_011534582 XR_942645 XR_942646 NR_026669 NM_001242792 NP_001229721 NM_001242793 NP_001229722 NM_001242794 NP_001229723 NM_001256717 NP_001243646 NM_001256718 NP_001243647 NM_014841 NP_055656
|
| Function |
Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}. Membrane, coated pit {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane. {ECO:0000250}.
|
![Western Blot: AP180 Overexpression Lysate (Adult Normal) [NBP2-10304] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AP180.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10320_AP180%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10304-img0001.jpg)