Gene Symbol | LAPTM5 |
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Entrez Gene | 7805 |
Alt Symbol | CLAST6 |
Species | Human |
Gene Type | protein-coding |
Description | lysosomal protein transmembrane 5 |
Other Description | CD40-ligand-activated specific transcripts|human retinoic acid-inducible E3 protein|lysosomal associated multispanning membrane protein 5|lysosomal multispanning membrane protein 5|lysosomal-associated multitransmembrane protein 5|lysosomal-associated transmembrane protein 5|retinoic acid-inducible E3 protein |
Swissprots | Q13240 Q13571 Q14698 Q3KP54 |
Accessions | EAX07640 EAX07641 Q13571 AF401210 AK292009 BAF84698 AK297014 BAG59547 BC106896 AAI06897 BC106897 AAI06898 BF000809 CT003824 D42042 BAA07643 U30498 AAA74018 U51240 AAB08975 XM_011542098 XP_011540400 NM_006762 NP_006753 |
Function | May have a special functional role during embryogenesis and in adult hematopoietic cells. {ECO:0000269|PubMed:8661146}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:8661146}; Multi-pass membrane protein {ECO:0000269|PubMed:8661146}. |
Tissue Specificity | Preferentially expressed in adult hematopoietic tissues. High levels in lymphoid and myeloid tissues. Highly expressed in peripheral blood leukocytes, thymus, spleen and lung, followed by placenta, liver and kidney. {ECO:0000269|PubMed:8661146}. |
Top Pathways | Lysosome |
LAPTM5 CRISPR/Cas9 KO Plasmid (h) - sc-404229 from Santa Cruz Biotechnology
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LAPTM5 HDR Plasmid (h) - sc-404229-HDR from Santa Cruz Biotechnology
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LAPTM5 Double Nickase Plasmid (h) - sc-404229-NIC from Santa Cruz Biotechnology
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LAPTM5 Double Nickase Plasmid (h2) - sc-404229-NIC-2 from Santa Cruz Biotechnology
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LAPTM5 CRISPR Activation Plasmid (h) - sc-404229-ACT from Santa Cruz Biotechnology
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LAPTM5 CRISPR Activation Plasmid (h2) - sc-404229-ACT-2 from Santa Cruz Biotechnology
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LAPTM5 Lentiviral Activation Particles (h) - sc-404229-LAC from Santa Cruz Biotechnology
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LAPTM5 Lentiviral Activation Particles (h2) - sc-404229-LAC-2 from Santa Cruz Biotechnology
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LAPTM5 siRNA (h) - sc-88756 from Santa Cruz Biotechnology
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LAPTM5 shRNA Plasmid (h) - sc-88756-SH from Santa Cruz Biotechnology
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LAPTM5 shRNA (h) Lentiviral Particles - sc-88756-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11548 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11548 from Sigma-Aldrich
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LAPTM5 siRNA (Human) - CRH5281 from Cohesion Biosciences
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shRNA set against Human LAPTM5 (NM_006762.2) - SHH328475 from Creative biogene
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Human LAPTM5 siRNA - orb265783 from Biorbyt
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LAPTM5 shRNA Plasmid (Human) - CHH5281 from Cohesion Biosciences
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LAPTM5 miRNA 3'UTR clone - MiUTR3H-04141 from Creative biogene
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