| Gene Symbol |
PIGA
|
| Entrez Gene |
5277
|
| Alt Symbol |
GPI3, MCAHS2, PIG-A, PNH1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylinositol glycan anchor biosynthesis, class A
|
| Other Description |
GLCNAC-PI synthesis protein|GPI anchor biosynthesis|class A GlcNAc-inositol phospholipid assembly protein|phosphatidylinositol N-acetylglucosaminyltransferase subunit A|phosphatidylinositol-glycan biosynthesis, class A protein
|
| Swissprots |
B4E0V2 P37287 Q16025 Q16250
|
| Accessions |
BAA05966 CAB57276 EAW98879 EAW98880 EAW98881 EAW98882 EAW98883 EAW98884 P37287 AK098047 BAG53569 AK290497 BAF83186 AK303538 BAG64564 AK304144 BAG65037 AK315063 BAG37537 BC038236 AAH38236 BM998465 BQ026877 CX870731 D11466 BAA02019 DA951065 DC347872 JF432189 ADZ15406 S61523 AAD13929 S74936 AAD14160 XM_011545539 XP_011543841 NM_002641 NP_002632 NM_020473 NP_065206 NR_033835 NR_033836 NM_020472
|
| Function |
Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Single-pass membrane protein.
|
| Top Pathways |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|