Gene Symbol | SLC25A25 |
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Entrez Gene | 114789 |
Alt Symbol | MCSC, PCSCL, SCAMC-2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 |
Other Description | calcium-binding mitochondrial carrier protein SCaMC-2|mitochondrial ATP-Mg/Pi carrier protein 3|mitochondrial Ca(2+)-dependent solute carrier protein 3|short calcium-binding mitochondrial carrier 2|small calcium-binding mitochondrial carrier 2|solute carrier family 25, member 25 |
Swissprots | Q6KCM7 Q5SYW8 Q5VWU2 Q96PZ1 Q6KCM6 Q5SYW7 Q6KCM4 Q9BSA6 Q6UX48 Q5SYX3 Q5VWU3 Q5VWU4 Q705K2 |
Accessions | EAW87738 EAW87739 Q6KCM7 AB067483 BAB67789 AJ619963 CAF04060 AJ619989 CAF04495 AJ619990 CAF04496 AJ619991 CAF04497 AJ619992 CAF04498 AK290705 BAF83394 AK290991 BAF83680 AL559911 AY358515 AAQ88879 BC005163 AAH05163 BC036889 BC044631 BC061925 BC089448 AAH89448 BC103930 AAI03931 BC103931 AAI03932 BC103932 AAI03933 BC103933 AAI03934 BM689843 BQ637100 BX642627 DA219774 XM_005251688 XP_005251745 XM_005251689 XP_005251746 XM_006716948 XP_006717011 XM_006716949 XP_006717012 NM_001006641 NP_001006642 NM_001006642 NP_001006643 NM_001265614 NP_001252543 NM_052901 NP_443133 NR_049766 NM_001006643 |
Function | Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. {ECO:0000269|PubMed:15123600}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600}; Multi- pass membrane protein {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600}. |
Tissue Specificity | Present in various cell lines (at protein level). Widely expressed. Expressed in fetal and adult liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus. Isoform 1 is present in all tissues tested. Isoform 2 expression is restricted to kidney and lung. {ECO:0000269|PubMed:15054102, ECO:0000269|PubMed:15123600}. |
SLC25A25 CRISPR/Cas9 KO Plasmid (h) - sc-407192 from Santa Cruz Biotechnology
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SLC25A25 HDR Plasmid (h) - sc-407192-HDR from Santa Cruz Biotechnology
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SLC25A25 Double Nickase Plasmid (h) - sc-407192-NIC from Santa Cruz Biotechnology
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SLC25A25 Double Nickase Plasmid (h2) - sc-407192-NIC-2 from Santa Cruz Biotechnology
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SLC25A25 CRISPR Activation Plasmid (h) - sc-407192-ACT from Santa Cruz Biotechnology
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SLC25A25 CRISPR Activation Plasmid (h2) - sc-407192-ACT-2 from Santa Cruz Biotechnology
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SLC25A25 Lentiviral Activation Particles (h) - sc-407192-LAC from Santa Cruz Biotechnology
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SLC25A25 Lentiviral Activation Particles (h2) - sc-407192-LAC-2 from Santa Cruz Biotechnology
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SLC25A25 siRNA (h) - sc-92973 from Santa Cruz Biotechnology
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SLC25A25 shRNA Plasmid (h) - sc-92973-SH from Santa Cruz Biotechnology
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SLC25A25 shRNA (h) Lentiviral Particles - sc-92973-V from Santa Cruz Biotechnology
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SLC25A25 RNAi - H00114789-R03 from Novus Biologicals
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SLC25A25 RNAi - H00114789-R01 from Novus Biologicals
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SLC25A25 RNAi - H00114789-R02 from Novus Biologicals
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MISSION® esiRNA - EHU070011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19494 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19494 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12751 from Sigma-Aldrich
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SLC25A25 siRNA (Human) - CRJ4375 from Cohesion Biosciences
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SLC25A25 RNAi - H00114789-R04 from Novus Biologicals
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SLC25A25 - MBS8217827 from MyBioSource
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shRNA set against Human SLC25A25 (NM_052901.4) - SHH409584 from Creative biogene
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SLC25A25 shRNA Plasmid (Human) - CHJ4375 from Cohesion Biosciences
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SLC25A25 miRNA 3'UTR clone - MiUTR3H-10192 from Creative biogene
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SLC25A25 miRNA 3'UTR clone - MiUTR3H-10193 from Creative biogene
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