Gene Symbol | Adm2 |
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Entrez Gene | 223780 |
Alt Symbol | Am2, IMD, Imdn |
Species | Mouse |
Gene Type | protein-coding |
Description | adrenomedullin 2 |
Other Description | ADM2|intermedin |
Swissprots | Q4VAE1 Q7TNK8 |
Accessions | EDL04357 EDL04358 Q7TNK8 AB121035 BAD07412 AF529212 AAQ09099 BB705319 BC096428 AAH96428 CJ052708 DV649647 NM_182928 NP_891558 |
Function | IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway. {ECO:0000269|PubMed:14615490, ECO:0000269|PubMed:14706825}. |
Subcellular Location | Secreted. |
Tissue Specificity | High expression detected in the submaxillary gland, kidney, stomach, and mesentery, followed by the pituitary, lung, pancreas, intestines, spleen, thymus and ovary. Expressed mainly in the intermediate lobe of the pituitary, with sporadic in the anterior lobe. {ECO:0000269|PubMed:14615490, ECO:0000269|PubMed:14706825}. |
Recombinant Mouse ADM2(Adm2) - CSB-YP759721MO CSB-EP759721MO CSB-BP759721MO CSB-MP759721MO from Cusabio
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ADM2(Adm2) - MBS1306760 from MyBioSource
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Recombinant Mouse ADM2 Protein - ADM2-1366M from Creative Biomart
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