Gene Symbol | SEMA3D |
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Entrez Gene | 223117 |
Alt Symbol | Sema-Z2, coll-2 |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D |
Other Description | collapsin 2|semaphorin-3D |
Swissprots | Q6UW77 O95025 Q8NCQ1 A6NK46 |
Accessions | EAL24184 EAW76974 EAW76975 EAW76976 EAW76977 O95025 AK021802 AK309116 AY358937 AAQ89296 BC029590 AAH29590 BX648652 DQ891565 ABM82491 DQ894753 ABM85679 XM_011515960 XP_011514262 XM_011515961 XP_011514263 XM_011515962 XP_011514264 NM_152754 NP_689967 |
Function | Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Axon guidance |
SEMA3D CRISPR/Cas9 KO Plasmid (h) - sc-403924 from Santa Cruz Biotechnology
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SEMA3D HDR Plasmid (h) - sc-403924-HDR from Santa Cruz Biotechnology
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SEMA3D Double Nickase Plasmid (h) - sc-403924-NIC from Santa Cruz Biotechnology
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SEMA3D Double Nickase Plasmid (h2) - sc-403924-NIC-2 from Santa Cruz Biotechnology
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SEMA3D CRISPR Activation Plasmid (h) - sc-403924-ACT from Santa Cruz Biotechnology
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SEMA3D CRISPR Activation Plasmid (h2) - sc-403924-ACT-2 from Santa Cruz Biotechnology
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SEMA3D Lentiviral Activation Particles (h) - sc-403924-LAC from Santa Cruz Biotechnology
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SEMA3D Lentiviral Activation Particles (h2) - sc-403924-LAC-2 from Santa Cruz Biotechnology
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SEMA3D siRNA (h) - sc-62992 from Santa Cruz Biotechnology
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SEMA3D shRNA Plasmid (h) - sc-62992-SH from Santa Cruz Biotechnology
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SEMA3D shRNA (h) Lentiviral Particles - sc-62992-V from Santa Cruz Biotechnology
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SEMA3D RNAi - H00223117-R02 from Novus Biologicals
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MISSION® esiRNA - EHU035221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19066 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19066 from Sigma-Aldrich
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SEMA3D siRNA (Human) - CRJ6590 from Cohesion Biosciences
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SEMA3D - MBS8203439 from MyBioSource
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shRNA set against Human SEMA3D (NM_152754.2) - SHH404220 from Creative biogene
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Human SEMA3D siRNA - orb277091 from Biorbyt
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SEMA3D shRNA Plasmid (Human) - CHJ6590 from Cohesion Biosciences
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SEMA3D miRNA 3'UTR clone - MiUTR1H-09251 from Creative biogene
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