| Gene Symbol |
GFPT1
|
| Entrez Gene |
2673
|
| Alt Symbol |
CMSTA1, GFA, GFAT, GFAT 1, GFAT1, GFAT1m, GFPT, GFPT1L, MSLG
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutamine--fructose-6-phosphate transaminase 1
|
| Other Description |
D-fructose-6-phosphate amidotransferase 1|glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1|glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1|glutamine:fructose-6-phosphate amidotransferase 1|hexosephosphate aminotransferase 1
|
| Swissprots |
Q9BXF8 Q53QE6 Q06210
|
| Accessions |
AAY14827 EAW99851 EAW99852 EAW99853 Q06210 AF131846 AF334737 AAK15342 AF445027 AAL38588 AW079566 BC045641 AAH45641 BG723175 BI560595 BM744371 DB133199 M90516 AAA58502 NM_001244710 NP_001231639 NM_002056 NP_002047
|
| Function |
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.
|
| Tissue Specificity |
Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. {ECO:0000269|PubMed:11679416}.
|
| Top Pathways |
Amino sugar and nucleotide sugar metabolism, Alanine, aspartate and glutamate metabolism
|