Gene Symbol |
EMILIN2
|
Entrez Gene |
84034
|
Alt Symbol |
EMILIN-2, FOAP-10
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
elastin microfibril interfacer 2
|
Other Description |
EMILIN-2|elastin microfibril interface-located protein 2|extracellular glycoprotein EMILIN-2
|
Swissprots |
Q9BXX0 Q8NBH3 Q96JQ4 B2RMY3
|
Accessions |
EAX01690 Q9BXX0 AB026706 BAB61020 AF270513 AAK37963 AI356740 AK090519 BAC03470 AL552384 BC032231 AAH32231 BC136541 AAI36542 BX398832 DQ590092 XM_011525747 XP_011524049 XM_011525748 XP_011524050 XR_935070 NM_032048 NP_114437
|
Function |
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix. Note=Found mainly at the interface between amorphous elastin and microfibrils.
|
Tissue Specificity |
Highest levels are present in fetal heart and adult lung. Intermediate levels in peripheral leukocytes, placenta, and spinal cord and low expression in fetal brain, spleen, thymus, and lung and in adult heart, aorta, testis, bone marrow, small intestine, thymus, lymph node, and appendix.
|