EPN2
| Gene Symbol | EPN2 |
|---|---|
| Entrez Gene | 22905 |
| Alt Symbol | EHB21 |
| Species | Human |
| Gene Type | protein-coding |
| Description | epsin 2 |
| Other Description | EPS-15-interacting protein 2|Eps15 binding protein|epsin-2 |
| Swissprots | Q9UPT7 B3KRX8 O95207 Q9H7Z2 E9PBC2 O95208 A8MTV8 Q52LD0 |
| Accessions | EAW50875 EAW50876 EAW50877 O95208 AB028988 BAA83017 AF062084 AAC78608 AF062085 AAC78609 AK001491 BAG50925 AK001996 BAG51000 AK024115 BAB14831 AK092366 BAG52540 AK295652 BAH12141 AK298006 BAH12703 AK307455 BC015488 BC051793 BC070036 AAH70036 BC093972 AAH93972 BC093974 AAH93974 BC143263 BC143264 AAI43265 DA220261 DC316524 NM_001102664 NP_001096134 NM_014964 NP_055779 NM_148921 NP_683723 |
| Function | Plays a role in the formation of clathrin-coated invaginations and endocytosis. {ECO:0000269|PubMed:10567358}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10567358}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:10567358}. Note=In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex. |
| Tissue Specificity | Highest expression is found in brain. Detected at lower levels in lung and liver. {ECO:0000269|PubMed:10567358}. |
| Top Pathways | Endocytosis |
epsin 2 CRISPR/Cas9 KO Plasmid (h) - sc-404716 from Santa Cruz Biotechnology
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epsin 2 HDR Plasmid (h) - sc-404716-HDR from Santa Cruz Biotechnology
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epsin 2 Double Nickase Plasmid (h) - sc-404716-NIC from Santa Cruz Biotechnology
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epsin 2 Double Nickase Plasmid (h2) - sc-404716-NIC-2 from Santa Cruz Biotechnology
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epsin 2 CRISPR Activation Plasmid (h) - sc-404716-ACT from Santa Cruz Biotechnology
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epsin 2 CRISPR Activation Plasmid (h2) - sc-404716-ACT-2 from Santa Cruz Biotechnology
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epsin 2 Lentiviral Activation Particles (h) - sc-404716-LAC from Santa Cruz Biotechnology
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epsin 2 Lentiviral Activation Particles (h2) - sc-404716-LAC-2 from Santa Cruz Biotechnology
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epsin 2 siRNA (h) - sc-40511 from Santa Cruz Biotechnology
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epsin 2 shRNA Plasmid (h) - sc-40511-SH from Santa Cruz Biotechnology
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epsin 2 shRNA (h) Lentiviral Particles - sc-40511-V from Santa Cruz Biotechnology
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Epsin-2 RNAi - H00022905-R02 from Novus Biologicals
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Epsin-2 RNAi - H00022905-R01 from Novus Biologicals
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MISSION® esiRNA - EHU087821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7927 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7927 from Sigma-Aldrich
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EPN2 siRNA (Human) - CRH7860 from Cohesion Biosciences
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Epsin-2 RNAi - H00022905-R03 from Novus Biologicals
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EPN2 - MBS8219993 from MyBioSource
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shRNA set against Human EPN2 (NM_014964.4) - SHH286581 from Creative biogene
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shRNA set against Human EPN2(NM_014964.4) - SHH036731 from Creative biogene
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shRNA set against Human EPN2(NM_148921.3) - SHH036737 from Creative biogene
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shRNA set against Human EPN2(NM_014964.4) - SHH036755 from Creative biogene
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Human EPN2 siRNA - orb268362 from Biorbyt
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EPN2 shRNA Plasmid (Human) - CHH7860 from Cohesion Biosciences
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