Gene Symbol | GALNTL5 |
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Entrez Gene | 168391 |
Alt Symbol | GALNACT19, GALNT15, GalNAc-T5L |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase-like 5 |
Other Description | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 15|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5|galNAc-T15|inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5|polypeptide GalNAc transferase 15|polypeptide GalNAc transferase-like 5|pp-GaNTase 15|protein-UDP acetylgalactosaminyltransferase 15|putative polypeptide N-acetylgalactosaminyltransferase-like protein 5 |
Swissprots | Q8NCV4 Q75MD3 Q7Z4T8 Q9UDR9 Q8WW05 Q75KN2 |
Accessions | AAD45823 AAS07428 AAS07457 EAL24517 EAW53977 EAW53978 EAW53979 EAW53980 EAW53981 Q7Z4T8 AF440400 AAM20912 AF440404 AAP97318 AK093091 AK315667 AW103179 BC022021 AAH22021 BC025391 DB022678 DQ890789 ABM81715 DQ893945 ABM84871 XM_006715862 XP_006715925 XM_011515848 XP_011514150 XM_011515849 XP_011514151 XM_011515850 XP_011514152 XM_011515851 XP_011514153 XM_011515852 XP_011514154 XM_011515853 XP_011514155 XM_011515854 XP_011514156 NM_145292 NP_660335 NR_033169 |
Function | Probable inactive glycosyltransferase required during spermatid development. May participate to protein loading into the acrosomes and accumulation of ubiquitin-proteasome systems around the head-tail coupling apparatus region. |
Subcellular Location | Late endosome membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=Localizes to the juxtanuclear region, possibly the late endosome. Not localized in the Golgi apparatus in round spermatids (By similarity). {ECO:0000250}. |
Tissue Specificity | Mainly expressed in testis. Weakly or not expressed in other tissues. {ECO:0000269|PubMed:24398516}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-TL5 CRISPR/Cas9 KO Plasmid (h) - sc-414905 from Santa Cruz Biotechnology
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GalNAc-TL5 HDR Plasmid (h) - sc-414905-HDR from Santa Cruz Biotechnology
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GalNAc-TL5 Double Nickase Plasmid (h) - sc-414905-NIC from Santa Cruz Biotechnology
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GalNAc-TL5 Double Nickase Plasmid (h2) - sc-414905-NIC-2 from Santa Cruz Biotechnology
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GalNAc-TL5 CRISPR Activation Plasmid (h) - sc-414905-ACT from Santa Cruz Biotechnology
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GalNAc-TL5 CRISPR Activation Plasmid (h2) - sc-414905-ACT-2 from Santa Cruz Biotechnology
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GalNAc-TL5 Lentiviral Activation Particles (h) - sc-414905-LAC from Santa Cruz Biotechnology
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GalNAc-TL5 Lentiviral Activation Particles (h2) - sc-414905-LAC-2 from Santa Cruz Biotechnology
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GalNAc-TL5 siRNA (h) - sc-89342 from Santa Cruz Biotechnology
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GalNAc-TL5 shRNA Plasmid (h) - sc-89342-SH from Santa Cruz Biotechnology
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GalNAc-TL5 shRNA (h) Lentiviral Particles - sc-89342-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU092341 from Sigma-Aldrich
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MISSION® esiRNA - EHU006811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9118 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9118 from Sigma-Aldrich
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GALNTL5 siRNA (Human) - CRJ6068 from Cohesion Biosciences
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GALNTL5 RNAi - H00168391-R01 from Novus Biologicals
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GALNTL5 - MBS8210797 from MyBioSource
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shRNA set against Human GALNTL5 (NM_145292.3) - SHH299149 from Creative biogene
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Human GALNTL5 siRNA - orb276569 from Biorbyt
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GALNTL5 shRNA Plasmid (Human) - CHJ6068 from Cohesion Biosciences
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