Gene Symbol | ESRRG |
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Entrez Gene | 2104 |
Alt Symbol | ERR3, ERRgamma, NR3B3 |
Species | Human |
Gene Type | protein-coding |
Description | estrogen-related receptor gamma |
Other Description | ERR gamma-2|estrogen receptor-related protein 3|nuclear receptor subfamily 3 group B member 3 |
Swissprots | P62508 E9PGB7 Q9UNJ4 Q6TS38 A8K4I0 A8K6I2 Q6PK28 Q68DA0 B3KY84 Q6P274 F8W8J3 |
Accessions | AAS00098 EAW93335 P62508 AA167816 AB020639 BAA74855 AB307715 BAH02306 AB362218 BAH36764 AF058291 AAC39899 AF094518 AAC99410 AF117255 AAD48370 AK001811 AK131193 BAG54746 AK290945 BAF83634 AK291028 BAF83717 AK291647 BAF84336 AK298851 BAH12885 AY388456 AAQ93376 AY388457 AAQ93377 AY388458 AAQ93378 AY388459 AAQ93379 AY388460 AAQ93380 AY388461 AAQ93381 BC008218 AAH08218 BC064700 AAH64700 BM723962 BP349857 BU752915 BX486063 BX647076 BX649009 CA397450 CF594270 CR749497 CAH18320 DA293919 DA720944 DA722064 DB220304 EU446472 ABZ92001 EU832476 ACE87648 EU832555 ACE86957 HQ692853 ADZ17364 HQ692854 ADZ17365 XM_006711205 XP_006711268 XM_011509265 XP_011507567 XM_011509266 XP_011507568 XM_011509267 XP_011507569 XM_011509268 XP_011507570 XM_011509269 XP_011507571 XM_011509270 XP_011507572 XM_011509271 XP_011507573 XM_011509272 XP_011507574 XM_011509273 XP_011507575 XM_011509274 XP_011507576 XM_011509275 XP_011507577 XM_011509276 XP_011507578 XM_011509277 XP_011507579 XM_011509278 XP_011507580 XM_011509279 XP_011507581 XM_011509280 XP_011507582 XM_011509281 XP_011507583 XM_011509282 XP_011507584 NM_001134285 NP_001127757 NM_001243505 NP_001230434 NM_001243506 NP_001230435 NM_001243507 NP_001230436 NM_001243509 NP_001230438 NM_001243510 NP_001230439 NM_001243511 NP_001230440 NM_001243512 NP_001230441 NM_001243513 NP_001230442 NM_001243514 NP_001230443 NM_001243515 NP_001230444 NM_001243518 NP_001230447 NM_001243519 NP_001230448 NM_001438 NP_001429 NM_206594 NP_996317 NM_206595 NP_996318 |
Function | Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle. {ECO:0000250, ECO:0000269|PubMed:11864604, ECO:0000269|PubMed:18063693, ECO:0000269|PubMed:19067653, ECO:0000269|PubMed:23836911}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland. {ECO:0000269|PubMed:14651967, ECO:0000269|PubMed:9676434}. |
ERRγ CRISPR/Cas9 KO Plasmid (h) - sc-416300 from Santa Cruz Biotechnology
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ERRγ HDR Plasmid (h) - sc-416300-HDR from Santa Cruz Biotechnology
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ERRγ Double Nickase Plasmid (h) - sc-416300-NIC from Santa Cruz Biotechnology
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ERRγ Double Nickase Plasmid (h2) - sc-416300-NIC-2 from Santa Cruz Biotechnology
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ERRγ CRISPR Activation Plasmid (h) - sc-416300-ACT from Santa Cruz Biotechnology
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ERRγ CRISPR Activation Plasmid (h2) - sc-416300-ACT-2 from Santa Cruz Biotechnology
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ERRγ Lentiviral Activation Particles (h) - sc-416300-LAC from Santa Cruz Biotechnology
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ERRγ Lentiviral Activation Particles (h2) - sc-416300-LAC-2 from Santa Cruz Biotechnology
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ERRγ siRNA (h) - sc-44704 from Santa Cruz Biotechnology
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ERRg shRNA Plasmid (h) - sc-44704-SH from Santa Cruz Biotechnology
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ERRg shRNA (h) Lentiviral Particles - sc-44704-V from Santa Cruz Biotechnology
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ERR gamma/NR3B3 RNAi - H00002104-R01 from Novus Biologicals
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ERR gamma/NR3B3 RNAi - H00002104-R03 from Novus Biologicals
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ERR gamma/NR3B3 RNAi - H00002104-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN7994 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7994 from Sigma-Aldrich
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ESRRG siRNA (Human) - CRH1461 from Cohesion Biosciences
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ESRRG - MBS8231434 from MyBioSource
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shRNA set against Human ESRRG (NM_001438.3) - SHH287473 from Creative biogene
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Human ESRRG siRNA - orb261963 from Biorbyt
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ESRRG shRNA Plasmid (Human) - CHH1461 from Cohesion Biosciences
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ESRRG miRNA 3'UTR clone - MiUTR4H-TG11148 from Creative biogene
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