Gene Symbol |
CXCR6
|
Entrez Gene |
10663
|
Alt Symbol |
BONZO, CD186, STRL33, TYMSTR
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chemokine (C-X-C motif) receptor 6
|
Other Description |
C-X-C chemokine receptor type 6|CDw186|CXC-R6|CXCR-6|G protein-coupled receptor|G-protein coupled receptor STRL33|G-protein coupled receptor bonzo
|
Swissprots |
O00574 Q9HCA5 O00575
|
Accessions |
AAG21918 AAP84356 ABK41924 ABV02579 CAC88555 EAW64754 O00574 AF007545 AAB64221 AK313754 BAG36493 BC033584 AAH33584 DQ892101 ABM83027 DQ895294 ABM86220 JC209412 CDM22047 U73529 AAB61456 U73530 U73531 AAB61457 Y13248 CAA73698 XM_005264809 XP_005264866 XM_011533290 XP_011531592 XM_011533291 XP_011531593 NM_006564 NP_006555
|
Function |
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed in lymphoid tissues and activated T cells.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway
|