| Gene Symbol |
LIPC
|
| Entrez Gene |
3990
|
| Alt Symbol |
HDLCQ12, HL, HTGL, LIPH
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lipase, hepatic
|
| Other Description |
hepatic lipase|hepatic triacylglycerol lipase|lipase member C
|
| Swissprots |
Q99465 A2RUB4 P78529 O43571 A8K9B6 P11150
|
| Accessions |
AAA59521 AAB60702 AAC34206 ABY81275 BAA11760 CDH61623 CDH93589 EAW77536 P11150 AI823349 AK290062 BAF82751 AK292631 BAF85320 AK293324 BAG56842 AK309448 AK315306 BAG37710 AV645541 BC132825 AAI32826 BC136495 AAI36496 BC146659 AAI46660 D83548 BAA12014 HQ258274 ADR83028 J03540 AAA59520 J03895 AAA61165 X07228 CAA30188 XM_005254372 XP_005254429 XM_005254374 XP_005254431 XM_006720502 XP_006720565 XM_011521551 XP_011519853 NM_000236 NP_000227
|
| Function |
Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Glycerolipid metabolism
|