Gene Symbol | RBFOX1 |
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Entrez Gene | 54715 |
Alt Symbol | 2BP1, A2BP1, FOX-1, FOX1, HRNBP1 |
Species | Human |
Gene Type | protein-coding |
Description | RNA binding protein, fox-1 homolog (C. elegans) 1 |
Other Description | RNA binding protein fox-1 homolog 1|ataxin 2-binding protein 1|fox-1 homolog A|fox-1-like RNA-binding protein 1|hexaribonucleotide-binding protein 1 |
Swissprots | Q9NS20 Q8TAF2 Q8WYB2 Q8TAE3 Q7Z7I7 Q9NWB1 |
Accessions | AAL83407 AAL83408 AAL83409 EAW85216 EAW85217 EAW85218 EAW85219 EAW85220 Q9NWB1 AB208826 BAD92063 AF094849 AAL83405 AF107203 AAF78291 AF109106 AAL83406 AF229057 AAL71904 AF448859 AAP41925 AK001027 BAA91472 AK293951 BAH11633 AK299664 BAH13094 AL713700 CAD28499 BC026312 BC033885 BC113691 AAI13692 BC143816 AAI43817 KJ534926 AHW56566 KJ535000 AHW56640 KJ535001 AHW56641 LN608588 XM_005255379 XP_005255436 XM_005255380 XP_005255437 XM_005255381 XP_005255438 XM_005255382 XP_005255439 XM_005255383 XP_005255440 XM_005255384 XP_005255441 XM_005255385 XP_005255442 XM_005255386 XP_005255443 XM_005255387 XP_005255444 XM_005255388 XP_005255445 XM_005255389 XP_005255446 XM_005255390 XP_005255447 XM_005255391 XP_005255448 XM_005255393 XP_005255450 XM_005255394 XP_005255451 XM_011522544 XP_011520846 XM_011522545 XP_011520847 XM_011522546 XP_011520848 XM_011522547 XP_011520849 XM_011522548 XP_011520850 NM_001142333 NP_001135805 NM_001142334 NP_001135806 NM_001308117 NP_001295046 NM_018723 NP_061193 NM_145891 NP_665898 NM_145892 NP_665899 NM_145893 NP_665900 |
Function | RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. {ECO:0000269|PubMed:16537540}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in muscle and brain. |
Fox-1 CRISPR/Cas9 KO Plasmid (h) - sc-405319 from Santa Cruz Biotechnology
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Fox-1 HDR Plasmid (h) - sc-405319-HDR from Santa Cruz Biotechnology
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Fox-1 Double Nickase Plasmid (h) - sc-405319-NIC from Santa Cruz Biotechnology
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Fox-1 Double Nickase Plasmid (h2) - sc-405319-NIC-2 from Santa Cruz Biotechnology
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Fox-1 CRISPR Activation Plasmid (h) - sc-405319-ACT from Santa Cruz Biotechnology
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Fox-1 CRISPR Activation Plasmid (h2) - sc-405319-ACT-2 from Santa Cruz Biotechnology
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Fox-1 Lentiviral Activation Particles (h) - sc-405319-LAC from Santa Cruz Biotechnology
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Fox-1 Lentiviral Activation Particles (h2) - sc-405319-LAC-2 from Santa Cruz Biotechnology
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Fox-1 siRNA (h) - sc-93015 from Santa Cruz Biotechnology
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Fox-1 shRNA Plasmid (h) - sc-93015-SH from Santa Cruz Biotechnology
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Fox-1 shRNA (h) Lentiviral Particles - sc-93015-V from Santa Cruz Biotechnology
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A2BP1 RNAi - H00054715-R01 from Novus Biologicals
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A2BP1 RNAi - H00054715-R03 from Novus Biologicals
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A2BP1 RNAi - H00054715-R04 from Novus Biologicals
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A2BP1 RNAi - H00054715-R02 from Novus Biologicals
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MISSION® esiRNA - EHU073021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18018 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18018 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10456 from Sigma-Aldrich
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RBFOX1 siRNA (Human) - CRJ0183 from Cohesion Biosciences
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RBFOX1 - MBS8235772 from MyBioSource
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shRNA set against Human RBFOX1 (NM_018723.3) - SHH390428 from Creative biogene
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Human RBFOX1 siRNA - orb270684 from Biorbyt
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RBFOX1 shRNA Plasmid (Human) - CHJ0183 from Cohesion Biosciences
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