NPHP3

Gene Symbol	NPHP3
Entrez Gene	27031
Alt Symbol	CFAP31, MKS7, NPH3, RHPD, RHPD1, SLSN3
Species	Human
Gene Type	protein-coding
Description	nephronophthisis 3 (adolescent)
Other Description	Meckel syndrome, type 7|cilia and flagella associated protein 31|nephrocystin-3
Swissprots	Q5JPE6 Q8N9R2 Q6NVH3 Q7Z493 Q68D99 Q96NK2 Q96N70 Q7Z494 Q5JPE3 Q8NCM5 Q7Z492
Accessions	CCQ43874 EAW79187 Q7Z494 AB056657 AI200954 AK055253 BAB70891 AK055893 BAB71038 AK092910 AK093012 BAC04018 AK094015 BAC04268 AL832863 CAI46200 AL832877 CAI46202 AY257864 AAP83423 AY257865 AAP83424 AY257866 AAP83425 BC063277 BC068082 AAH68082 BC131729 BC172279 AAI72279 CR749498 CAH18321 DB114822 EB387619 NM_153240 NP_694972
Function	Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements. {ECO:0000269|PubMed:18371931}.
Subcellular Location	Cell projection, cilium {ECO:0000269|PubMed:20462968, ECO:0000269|PubMed:22085962}. Note=Localization to cilium is mediated via interaction with UNC119 and UNC119B, which bind to the myristoyl moiety of the N- terminus.
Tissue Specificity	Widely expressed at low level. Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at very low level in brain and lung. {ECO:0000269|PubMed:12872122}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

nephrocystin-3 (C-19) - sc-49458 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

nephrocystin-3 (H-300) - sc-134745 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

nephrocystin-3 (N-18) - sc-49459 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

nephrocystin-3 (S-19) - sc-49461 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-NPHP3 antibody - ab121305 from Abcam Prices $443.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa144-173, AP) - LS-C264611 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa144-173, Biotin) - LS-C264613 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa144-173, APC) - LS-C264612 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa144-173, Azide-free, HRP) - LS-C264615 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa144-173, FITC) - LS-C264614 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa144-173, PE) - LS-C264616 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa151-181) - LS-C323413 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NPHP3 Antibody (aa144-173) - LS-C162961 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

NPHP3 Antibody - NBP1-83543 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

NPHP3 Antibody - 45760002 from Novus Biologicals Prices $299.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

NPHP3 Antibody (3B1) - H00027031-M05 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3B1

Anti-NPHP3 antibody produced in rabbit - HPA009150 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ANTI-NPHP3 (N-TERM) antibody produced in rabbit - SAB1303530 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

NPHP3-Antibody-N-term - AP12751a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

NPHP3 Antibody - N-terminal region (OAAB09033) - OAAB09033 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Nephrocystin 3 antibody - 22026-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

Nephrocystin 3 (N-term) antibody - AP52918PU-N from Acris Antibodies Prices $330.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Nephrocystin 3 antibody - H00027031-M05 from Acris Antibodies Prices $360.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3B1

NPHP3 antibody - 22026-1-AP from Proteintech Group Prices $279.00 Sizes con: 76 μg/150μl Host Rabbit Clonality Polyclonal

Anti-NPHP3 (aa 256-360) polyclonal antibody - DPABH-16531 from Creative Diagnostics Host Rabbit Clonality Polyclonal

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