Gene Symbol | DDX23 |
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Entrez Gene | 9416 |
Alt Symbol | PRPF28, SNRNP100, U5-100K, U5-100KD, prp28 |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 |
Other Description | 100 kDa U5 snRNP-specific protein|DEAD box protein 23|PRP28 homolog, yeast|PRP28p homolog|U5 snRNP 100 kD protein|probable ATP-dependent RNA helicase DDX23 |
Swissprots | B4DH15 B2R600 Q9BUQ8 O43188 |
Accessions | EAW58010 EAW58011 EAW58012 EAW58013 EAW58014 EAW58015 EAW58016 EAW58017 Q9BUQ8 AF026402 AAB87902 AK128428 BAG54673 AK292921 BAF85610 AK294877 BAG57976 AK312379 BAG35297 BC002366 AAH02366 CD709611 DQ891425 ABM82351 DQ894599 ABM85525 NM_004818 NP_004809 |
Function | Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation. {ECO:0000269|PubMed:18425142}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20858735, ECO:0000269|PubMed:9409622}. |
Top Pathways | Spliceosome |
DDX23 CRISPR/Cas9 KO Plasmid (h) - sc-407132 from Santa Cruz Biotechnology
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DDX23 HDR Plasmid (h) - sc-407132-HDR from Santa Cruz Biotechnology
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DDX23 Double Nickase Plasmid (h) - sc-407132-NIC from Santa Cruz Biotechnology
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DDX23 Double Nickase Plasmid (h2) - sc-407132-NIC-2 from Santa Cruz Biotechnology
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DDX23 CRISPR Activation Plasmid (h) - sc-407132-ACT from Santa Cruz Biotechnology
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DDX23 CRISPR Activation Plasmid (h2) - sc-407132-ACT-2 from Santa Cruz Biotechnology
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DDX23 Lentiviral Activation Particles (h) - sc-407132-LAC from Santa Cruz Biotechnology
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DDX23 Lentiviral Activation Particles (h2) - sc-407132-LAC-2 from Santa Cruz Biotechnology
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DDX23 siRNA (h) - sc-62200 from Santa Cruz Biotechnology
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DDX23 shRNA Plasmid (h) - sc-62200-SH from Santa Cruz Biotechnology
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DDX23 shRNA (h) Lentiviral Particles - sc-62200-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU054101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7046 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05783 from Sigma-Aldrich
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DDX23 siRNA (Human) - CRH6244 from Cohesion Biosciences
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DDX23 RNAi - H00009416-R02 from Novus Biologicals
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DDX23 - MBS8213729 from MyBioSource
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CompoZr ® Knockout ZFN Kit - CKOZFN7046 from Sigma-Aldrich
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shRNA set against Human DDX23 (NM_004818.2) - SHH275889 from Creative biogene
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shRNA set against Human DDX23(NM_004818.2) - SHG207487 from Creative biogene
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Human DDX23 siRNA - orb266746 from Biorbyt
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DDX23 shRNA Plasmid (Human) - CHH6244 from Cohesion Biosciences
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DDX23 miRNA 3'UTR clone - MiUTR1H-02728 from Creative biogene
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