Gene Symbol | HSF2 |
---|---|
Entrez Gene | 3298 |
Alt Symbol | HSF 2, HSTF 2 |
Species | Human |
Gene Type | protein-coding |
Description | heat shock transcription factor 2 |
Other Description | heat shock factor protein 2 |
Swissprots | B4DGJ4 Q03933 Q2M1K4 Q0VAH9 Q9H445 |
Accessions | ABF47087 CAM91163 CCQ43265 EAW48174 EAW48175 EAW48176 EAW48177 Q03933 AK225593 AK225594 AK294624 BAG57805 AK316377 BAH14748 BC005329 AAH05329 BC064622 AAH64622 BC112323 AAI12324 BC121050 AAI21051 BC121051 AAI21052 BC128420 AAI28421 DA741774 EU446897 ABZ92426 M65217 AAA36017 NM_001135564 NP_001129036 NM_001243094 NP_001230023 NM_004506 NP_004497 |
Function | DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:8339932}. Nucleus {ECO:0000269|PubMed:8339932}. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation. |