| Gene Symbol |
ANAPC15
|
| Entrez Gene |
25906
|
| Alt Symbol |
APC15, C11orf51, HSPC020
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
anaphase promoting complex subunit 15
|
| Other Description |
anaphase-promoting complex subunit 15
|
| Swissprots |
Q9Y269 G3V1Q3 Q9CXK2 P60006
|
| Accessions |
EAW74838 EAW74839 EAW74840 EAW74841 EAW74842 P60006 AF077206 AAD27001 AK222622 AK311146 AL080071 CAB45698 BC005156 AAH05156 BC005393 AAH05393 BE616852 BG752082 BG764016 BU532056 BU856100 BU930156 CD049337 CN306434 EU831644 ACE87244 EU831728 ACE86562 HQ447908 ADQ32392 HY080534 NM_001278485 NP_001265414 NM_001278486 NP_001265415 NM_001278487 NP_001265416 NM_001278488 NP_001265417 NM_001278489 NP_001265418 NM_001278490 NP_001265419 NM_001278491 NP_001265420 NM_001278492 NP_001265421 NM_001278493 NP_001265422 NM_001278494 NP_001265423 NM_014042 NP_054761
|
| Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20. {ECO:0000269|PubMed:21926987}.
|
![Western Blot: C11orf51 Overexpression Lysate (Adult Normal) [NBL1-08107] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C11orf51.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7617_C11orf51%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08107-img0002.jpg)