Gene Symbol | UNCX |
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Entrez Gene | 340260 |
Alt Symbol | UNCX4.1 |
Species | Human |
Gene Type | protein-coding |
Description | UNC homeobox |
Other Description | Unc4.1 homeobox|homeobox protein Uncx4.1|homeobox protein unc-4 homolog |
Swissprots | A4D221 A6NJT0 |
Accessions | A6NJT0 EAL23940 EAW87199 KM587717 AIY68497 KM587718 AIY68498 KM587719 AIY68499 NM_001080461 NP_001073930 |
Function | Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
UNCX CRISPR/Cas9 KO Plasmid (h) - sc-410425 from Santa Cruz Biotechnology
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UNCX HDR Plasmid (h) - sc-410425-HDR from Santa Cruz Biotechnology
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UNCX Double Nickase Plasmid (h) - sc-410425-NIC from Santa Cruz Biotechnology
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UNCX Double Nickase Plasmid (h2) - sc-410425-NIC-2 from Santa Cruz Biotechnology
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UNCX CRISPR Activation Plasmid (h) - sc-410425-ACT from Santa Cruz Biotechnology
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UNCX CRISPR Activation Plasmid (h2) - sc-410425-ACT-2 from Santa Cruz Biotechnology
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UNCX Lentiviral Activation Particles (h) - sc-410425-LAC from Santa Cruz Biotechnology
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UNCX Lentiviral Activation Particles (h2) - sc-410425-LAC-2 from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22508 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22508 from Sigma-Aldrich
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UNCX siRNA (Human) - CRJ7334 from Cohesion Biosciences
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UNCX - MBS8212234 from MyBioSource
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shRNA set against Human Uncx (NM_001080461.1) - SHH440668 from Creative biogene
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Human UNCX siRNA - orb277835 from Biorbyt
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UNCX shRNA Plasmid (Human) - CHJ7334 from Cohesion Biosciences
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UNCX miRNA 3'UTR clone - MiUTR1H-11018 from Creative biogene
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