MFSD2A

Gene Symbol MFSD2A
Entrez Gene 84879
Alt Symbol MFSD2, NLS1
Species Human
Gene Type protein-coding
Description major facilitator superfamily domain containing 2A
Other Description major facilitator superfamily domain-containing protein 2A|sodium-dependent LPC symporter 1|sodium-dependent lysophosphatidylcholine symporter 1
Swissprots Q96F59 A8K675 Q6UWU5 Q8NA29 Q9BRC8
Accessions CAF86469 EAX07246 EAX07247 EAX07248 EAX07249 Q8NA29 AB073383 BAD38634 AF289609 AAL55793 AF370364 AAQ15200 AK027396 AK074186 AK075183 BAC11456 AK093223 BAC04100 AK291540 BAF84229 AK297991 BAG60299 AK301533 BAG63034 AL834184 AY358636 AAQ88999 BC006353 AAH06353 BC011587 AAH11587 BC092414 AAH92414 BP321361 DB376308 DC297497 XM_005271285 XP_005271342 XM_011542312 XP_011540614 XR_946783 NM_001136493 NP_001129965 NM_001287808 NP_001274737 NM_001287809 NP_001274738 NM_032793 NP_116182 NR_109896
Function Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega- 3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport. Not required for central nervous system vascular morphogenesis (By similarity). Acts as a transporter for tunicamycin, an inhibitor of asparagine-linked glycosylation. In placenta, acts as a receptor for ERVFRD- 1/syncytin-2
Subcellular Location Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000305}. Note=Cytoplasmic punctae that may represent vesicles shuttling between the endoplasmic reticulum and the plasma membrane. {ECO:0000269|PubMed:21677192}.
Tissue Specificity In placenta, associated with trophoblast cells. {ECO:0000269|PubMed:18988732}.

MFSD2 (H-130) - sc-135305 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MFSD2 (H-130): sc-135305. Western blot analysis of MFSD2 expression in THP-1 whole cell lysate.

MFSD2 (N-12) - sc-163084 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MFSD2A antibody - ab105399 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-MFSD2A antibody (ab105399) at 1 µg/mlLane 2 : Anti-MFSD2A antibody (ab105399) at 2 µg/mlLane 1 : Rat lung tissue lysate Lane 2 : Rat lung tissue lysate Lysates/proteins at 15 µg per lane.

Anti-MFSD2A antibody - ab117618 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab117618, at 5 µg/ml, staining MFSD2A in Formalin-fixed, Paraffin-embedded Human Brain, Cerebellum tissue by Immunohistochemistry.

MFSD2 Antibody - NBP1-92112 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MFSD2 Antibody [NBP1-92112] - Staining of human cell line A-431 shows positivity in plasma membrane and cytoplasm. Antibody staining is shown in green.

MFSD2A Polyclonal Antibody - bs-6073R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti MFSD2A Polyclonal Antibody, Unconjugated (bs-6073R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-MFSD2A antibody produced in rabbit - HPA043107 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MFSD2A: <B>Cat. No. HPA043107</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Anti-MFSD2A antibody produced in rabbit - SAB2900890 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MFSD2A (C-Terminus), antibody produced in rabbit: <B>Cat. No. SAB2900890</B>: Anti-MFSD2A antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 μg/mL.

MFSD2A Antibody - N-terminal region (ARP50119_P050) - ARP50119_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MFSD2A antibody - GTX51685 from GeneTex

Prices $319.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Anti-MFSD2A antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX51685

MFSD2A antibody - GTX85147 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-MFSD2A antibody used in Western blot. GTX85147

MFSD2A antibody - orb75514 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat lung tissue lysate at (A) 1 and (B) 2 ug/mL using MFSD2A antibody

MFSD2A Antibody (OABF01648) - OABF01648 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MFSD2 antibody - 25498-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human testis tissue slide using 25498-1-AP( MFSD2 Antibody) at dilution of 1:50 (under 40x lens)

MFSD2 (C-term) antibody - AP26290PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of MFSD2A in rat lung tissue lysate with MFSD2A antibody at (A) 1 and (B) 2 μg/ml.

MFSD2 (C-term) antibody - AP31248PU-N from Acris Antibodies

Prices $430.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

MFSD2A Antibody - 6025 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of MFSD2A in rat lung tissue lysate with MFSD2A antibody at (A) 1 and (B) 2 μg/mL.

MFSD2 antibody - 25498-1-AP from Proteintech Group

Prices $279.00
Sizes con: 60 μg/150μl
Host Rabbit
Clonality Polyclonal
HepG2 cells were subjected to SDS PAGE followed by western blot with 25498-1-AP( MFSD2 Antibody) at dilution of 1:1000

MFSD2A Antibody - 37724 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Gel: 8%SDS-PAGE Lysates (from left to right): Human thyroid cancer tissue Amount of lysate: 40ug per lane Primary antibody: 1/250 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute

MFSD2A Polyclonal Antibody - ESAP13660 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of Human thyroid cancer tissue, using MFSD2A Polyclonal Antibody at dilution of 1:250

MFSD2A Polyclonal Antibody - ESAP16967 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of Human thyroid cancer, mouse liver and human fetal liver tissue, A549 and 293T cell, using MFSD2A Polyclonal Antibody at dilution of 1:300

Anti-MFSD2A (C-terminal) polyclonal antibody - DPABH-06512 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-MFSD2A (aa 183-232) polyclonal antibody - DPABH-12577 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal
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