| Gene Symbol |
MXD3
|
| Entrez Gene |
83463
|
| Alt Symbol |
BHLHC13, MAD3, MYX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAX dimerization protein 3
|
| Other Description |
Max-associated protein 3|Max-interacting transcriptional repressor MAD3|class C basic helix-loop-helix protein 13|max dimerization protein 3|max dimerizer 3
|
| Swissprots |
Q53HK1 Q96ME3 Q7Z4Y0 Q9BW11 Q8NDJ7 B4E0J1
|
| Accessions |
EAW85016 EAW85017 EAW85018 EAW85019 EAW85020 Q9BW11 AF114834 AAP97233 AK057034 BAB71352 AK092842 BAC03987 AK222579 BAD96299 AK303397 BAG64453 AK316468 BAH14839 AL522759 AL833959 CAD38809 BC000745 AAH00745 BC032586 AAH32586 BC041690 BM849150 BU620484 DQ892734 ABM83660 DQ895981 ABM86907 DQ896213 ABM87212 NM_001142935 NP_001136407 NM_031300 NP_112590
|
| Function |
Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
|