Gene Symbol | ADAMTS7 |
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Entrez Gene | 11173 |
Alt Symbol | ADAM-TS 7, ADAM-TS7, ADAMTS-7 |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
Other Description | A disintegrin and metalloproteinase with thrombospondin motifs 7|COMPase|a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 |
Swissprots | Q6P7J9 Q9UKP4 Q14F51 |
Accessions | EAW99148 EAW99149 EAW99150 EAW99151 Q9UKP4 AB209497 BAD92734 AF140675 AAD56358 AK299844 BAG61706 AL110226 CAB53684 AL359934 CAB95770 AY327122 AAQ94616 BC061631 AAH61631 CB991707 XM_005254137 XP_005254194 XM_011521166 XP_011519468 NM_014272 NP_055087 |
Function | Metalloprotease that may play a role in the degradation of COMP. {ECO:0000269|PubMed:16585064}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Also found associated with the external cell surface. {ECO:0000250}. |
Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments. {ECO:0000269|PubMed:15192113, ECO:0000269|PubMed:16585064}. |
ADAMTS-7 CRISPR/Cas9 KO Plasmid (h) - sc-403381 from Santa Cruz Biotechnology
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ADAMTS-7 HDR Plasmid (h) - sc-403381-HDR from Santa Cruz Biotechnology
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ADAMTS-7 Double Nickase Plasmid (h) - sc-403381-NIC from Santa Cruz Biotechnology
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ADAMTS-7 Double Nickase Plasmid (h2) - sc-403381-NIC-2 from Santa Cruz Biotechnology
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ADAMTS-7 CRISPR Activation Plasmid (h) - sc-403381-ACT from Santa Cruz Biotechnology
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ADAMTS-7 CRISPR Activation Plasmid (h2) - sc-403381-ACT-2 from Santa Cruz Biotechnology
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ADAMTS-7 Lentiviral Activation Particles (h) - sc-403381-LAC from Santa Cruz Biotechnology
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ADAMTS-7 Lentiviral Activation Particles (h2) - sc-403381-LAC-2 from Santa Cruz Biotechnology
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ADAMTS-7 siRNA (h) - sc-89955 from Santa Cruz Biotechnology
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ADAMTS-7 shRNA Plasmid (h) - sc-89955-SH from Santa Cruz Biotechnology
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ADAMTS-7 shRNA (h) Lentiviral Particles - sc-89955-V from Santa Cruz Biotechnology
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ADAMTS7 RNAi - H00011173-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2392 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2392 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02242 from Sigma-Aldrich
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ADAMTS7 siRNA (Human) - CRH7654 from Cohesion Biosciences
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ADAMTS7 - MBS8238446 from MyBioSource
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ADAMTS-7 CRISPR/Cas9 KO Plasmid (h2) - sc-403381-KO-2 from Santa Cruz Biotechnology
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ADAMTS-7 HDR Plasmid (h2) - sc-403381-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ADAMTS7 (NM_014272.3) - SHH231910 from Creative biogene
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shRNA set against Human ADAMTS7(NM_014272.3) - SHG040065 from Creative biogene
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ADAMTS7 shRNA Plasmid (Human) - CHH7654 from Cohesion Biosciences
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ADAMTS7 miRNA 3'UTR clone - MiUTR1H-00176 from Creative biogene
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