ARNTL2

Gene Symbol ARNTL2
Entrez Gene 56938
Alt Symbol BMAL2, CLIF, MOP9, PASD9, bHLHe6
Species Human
Gene Type protein-coding
Description aryl hydrocarbon receptor nuclear translocator-like 2
Other Description CYCLE-like factor|PAS domain-containing protein 9|aryl hydrocarbon receptor nuclear translocator-like protein 2|basic-helix-loop-helix-PAS protein MOP9|brain and muscle ARNT-like 2|class E basic helix-loop-helix protein 6|member of PAS protein 9|transcription factor BMAL2
Swissprots Q96J63 Q9NS70 Q8WYA1 Q8WYA4 Q8WYA2 B7Z429 Q9NYQ5 Q8WYA3 Q9NYQ4 Q9H2M4 F5H402
Accessions CAV28553 EAW96552 EAW96553 EAW96554 Q8WYA1 AB039921 BAB01485 AF231338 AAF71306 AF231339 AAF71307 AF246960 AAL50339 AF246961 AAL50340 AF246962 AAL50341 AF246963 AAL50342 AF256215 AAG34652 AK296706 BAH12415 BC000172 AAH00172 BC125061 AAI25062 BC125062 AAI25063 BQ774827 CV388040 XM_006719112 XP_006719175 XM_006719113 XP_006719176 XM_006719114 XP_006719177 XM_011520766 XP_011519068 XM_011520767 XP_011519069 XM_011520768 XP_011519070 XM_011520769 XP_011519071 XM_011520770 XP_011519072 XM_011520771 XP_011519073 NM_001248002 NP_001234931 NM_001248003 NP_001234932 NM_001248004 NP_001234933 NM_001248005 NP_001234934 NM_020183 NP_064568
Function Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time- keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:10964693}.
Tissue Specificity Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala. {ECO:0000269|PubMed:10864977, ECO:0000269|PubMed:10964693, ECO:0000269|PubMed:11018023}.

BMAL2 (C-7) - sc-376287 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BMAL2 (C-7): sc-376287. Western blot analysis of BMAL2 expression in JAR whole cell lysate.

BMAL2 (H-166) - sc-98300 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BMAL2 (H-166): sc-98300. Western blot analysis of BMAL2 expression in non-transfected: sc-110760 (A) and human BMAL2 transfected: sc-110662 (B) 293 whole cell lysates.

BMAL2 (C-11) - sc-365469 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BMAL2 (C-11): sc-365469. Western blot analysis of BMAL2 expression in non-transfected: sc-110760 (A) and human BMAL2 transfected: sc-110662 (B) 293 whole cell lysates.

BMAL2 (K-12) - sc-109217 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BMAL2 (K-12): sc-109217. Western blot analysis of human recombinant BMAL2 fusion protein.

BMAL2 (M-52) - sc-98377 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BMAL2 (M-52): sc-98377. Western blot analysis of BMAL2 expression in 293 whole cell lysate.

BMAL2 (S-14) - sc-109219 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BMAL2 (S-14): sc-109219. Western blot analysis of human recombinant BMAL2 fusion protein.

BMAL2 (T-12) - sc-109220 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ARNTL2 antibody [EPR16389] - ab198293 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16389
All lanes : Anti-ARNTL2 antibody [EPR16389] (ab198293) at 1/2000 dilutionLane 1 : MCF7 (Human breast adenocarcinoma cell line) cell lysateLane 2 : JAR (Human placenta choriocarcinoma cell line) cell lysateLane 3 : HeLa (Human epithelial cells from cervix adenocarcinoma) cell lysateLane 4 : 293 (Human epithelial cells from embryonic kidney) cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-BMAL2 / ARNTL2 Antibody - LS-C69291 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-BMAL2 / ARNTL2 Antibody (aa329-378) - LS-C134949 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ARNTL2 antibody LS-C134949 Western blot of Mouse Heart lysate.

Anti-BMAL2 / ARNTL2 Antibody (C-Terminus) - LS-C135078 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ARNTL2 antibody LS-C135078 Western blot of Mouse Kidney lysate.

Anti-BMAL2 / ARNTL2 Antibody (clone ARNTH6B5) - LS-C184275 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone ARNTH6B5
Immunofluorescent staining using ARNTL2 antibody. Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-ARNTL2 antibody.

Anti-BMAL2 / ARNTL2 Antibody (aa35-84) IHC-plus™ - LS-B6621 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ARNTL2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6621 concentration 5 ug/ml.

Anti-BMAL2 / ARNTL2 Antibody (clone ARNTH6B5) - LS-C342828 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone ARNTH6B5
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-ARNTL2 mAb.

ARNTL2 Antibody - NBP2-32423 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2 Antibody - NB100-75238 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-CLIF)

ARNTL2/BMAL2 Polyclonal Antibody - bs-11446R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11446R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11446R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11446R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11446R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, Cy3 Conjugated - bs-11446R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, Cy5 Conjugated - bs-11446R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11446R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ARNTL2/BMAL2 Polyclonal Antibody, Cy7 Conjugated - bs-11446R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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