| Gene Symbol |
RNF167
|
| Entrez Gene |
26001
|
| Alt Symbol |
5730408C10Rik, LP2254, RING105
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 167
|
| Other Description |
E3 ubiquitin-protein ligase RNF167
|
| Swissprots |
D3DTK8 Q9H6Y7 Q9Y3V1 Q8NDC1 Q6XYE0
|
| Accessions |
EAW90385 EAW90386 EAW90387 EAW90388 Q9H6Y7 AK025329 BAB15113 AL050060 CAB43253 AL079315 CAB45281 AL834284 CAD38958 AY203930 AAP34453 AY960626 BC010139 AAH10139 BC013222 CR457340 CAG33621 XM_005256599 XP_005256656 XM_005256603 XP_005256660 XM_011523787 XP_011522089 XM_011523788 XP_011522090 XM_011523789 XP_011522091 XM_011523790 XP_011522092 XM_011523791 XP_011522093 XM_011523792 XP_011522094 NM_015528 NP_056343
|
| Function |
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition. {ECO:0000269|PubMed:16314844}.
|
| Subcellular Location |
Endomembrane system {ECO:0000269|PubMed:16314844}; Single-pass membrane protein {ECO:0000269|PubMed:16314844}. Note=Targeted to cytoplasmic membranes.
|
| Tissue Specificity |
Strongly expressed in the kidney and liver (at protein level). {ECO:0000269|PubMed:16314844}.
|
![Western Blot: RNF167 Overexpression Lysate (Adult Normal) [NBP2-07157] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RNF167.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8481_RNF167%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07157-img0001.jpg)