IDS

Gene Symbol IDS
Entrez Gene 3423
Alt Symbol MPS2, SIDS
Species Human
Gene Type protein-coding
Description iduronate 2-sulfatase
Other Description alpha-L-iduronate sulfate sulfatase|iduronate 2-sulfatase 14 kDa chain|iduronate 2-sulfatase 42 kDa chain|idursulfase
Swissprots P22304 D3DWT4 Q9BRM3 Q14604
Accessions AAA16877 AAA59192 AAB64180 AAC77828 CBX51378 CDL93518 EAW61280 EAW61281 EAW61282 EAW61283 EAW61284 EAW61285 P22304 AF050145 AAC05984 AI242974 AK055600 AK057191 AK294541 BAG57748 AK295815 BAG58633 AL117536 BC006170 AAH06170 BX647357 BY996633 CN303532 DA325538 DA351886 DB500211 EF363095 L40586 AAA92014 M58342 AAA63197 NM_000202 NP_000193 NM_001166550 NP_001160022 NM_006123 NP_006114 NR_104128
Function Required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
Subcellular Location Lysosome.
Tissue Specificity Liver, kidney, lung, and placenta.
Top Pathways Lysosome, Glycosaminoglycan degradation