Gene Symbol | IDS |
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Entrez Gene | 3423 |
Alt Symbol | MPS2, SIDS |
Species | Human |
Gene Type | protein-coding |
Description | iduronate 2-sulfatase |
Other Description | alpha-L-iduronate sulfate sulfatase|iduronate 2-sulfatase 14 kDa chain|iduronate 2-sulfatase 42 kDa chain|idursulfase |
Swissprots | P22304 D3DWT4 Q9BRM3 Q14604 |
Accessions | AAA16877 AAA59192 AAB64180 AAC77828 CBX51378 CDL93518 EAW61280 EAW61281 EAW61282 EAW61283 EAW61284 EAW61285 P22304 AF050145 AAC05984 AI242974 AK055600 AK057191 AK294541 BAG57748 AK295815 BAG58633 AL117536 BC006170 AAH06170 BX647357 BY996633 CN303532 DA325538 DA351886 DB500211 EF363095 L40586 AAA92014 M58342 AAA63197 NM_000202 NP_000193 NM_001166550 NP_001160022 NM_006123 NP_006114 NR_104128 |
Function | Required for the lysosomal degradation of heparan sulfate and dermatan sulfate. |
Subcellular Location | Lysosome. |
Tissue Specificity | Liver, kidney, lung, and placenta. |
Top Pathways | Lysosome, Glycosaminoglycan degradation |
IDS CRISPR/Cas9 KO Plasmid (h) - sc-404268 from Santa Cruz Biotechnology
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IDS HDR Plasmid (h) - sc-404268-HDR from Santa Cruz Biotechnology
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IDS Double Nickase Plasmid (h) - sc-404268-NIC from Santa Cruz Biotechnology
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IDS Double Nickase Plasmid (h2) - sc-404268-NIC-2 from Santa Cruz Biotechnology
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IDS CRISPR Activation Plasmid (h) - sc-404268-ACT from Santa Cruz Biotechnology
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IDS CRISPR Activation Plasmid (h2) - sc-404268-ACT-2 from Santa Cruz Biotechnology
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IDS Lentiviral Activation Particles (h) - sc-404268-LAC from Santa Cruz Biotechnology
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IDS Lentiviral Activation Particles (h2) - sc-404268-LAC-2 from Santa Cruz Biotechnology
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IDS siRNA (h) - sc-90917 from Santa Cruz Biotechnology
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IDS shRNA Plasmid (h) - sc-90917-SH from Santa Cruz Biotechnology
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IDS shRNA (h) Lentiviral Particles - sc-90917-V from Santa Cruz Biotechnology
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Iduronate 2-Sulfatase/IDS RNAi - H00003423-R02 from Novus Biologicals
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Iduronate 2-Sulfatase/IDS RNAi - H00003423-R01 from Novus Biologicals
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MISSION® esiRNA - EHU059341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1649 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1649 from Sigma-Aldrich
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IDS siRNA (Human) - CRH2318 from Cohesion Biosciences
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IDS - MBS8206112 from MyBioSource
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shRNA set against Human IDS (NM_000202.5) - SHH316665 from Creative biogene
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IDS shRNA Plasmid (Human) - CHH2318 from Cohesion Biosciences
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IDS miRNA 3'UTR clone - MiUTR3H-02945 from Creative biogene
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