Gene Symbol | DYNLL1 |
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Entrez Gene | 8655 |
Alt Symbol | DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, PIN, hdlc1 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, light chain, LC8-type 1 |
Other Description | 8 kDa dynein light chain|cytoplasmic dynein light polypeptide|dynein light chain 1, cytoplasmic|dynein, cytoplasmic, light polypeptide 1|protein inhibitor of neuronal nitric oxide synthase |
Swissprots | P63167 |
Accessions | EAW98195 EAW98196 EAW98197 P63167 AK309022 AK311790 BAG34733 BC100289 AAI00290 BC104244 AAI04245 BC104245 AAI04246 BG474448 BG705617 BI491360 BM817665 BU598428 CB992195 CD678447 CR407672 CAG28600 CR542128 CAG46925 GQ129277 ACT64411 GQ129278 ACT64412 U32944 AAB04149 NM_001037494 NP_001032583 NM_001037495 NP_001032584 NM_003746 NP_003737 |
Function | Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. |
Subcellular Location | Cytoplasm, cytoskeleton. Nucleus. Mitochondrion. Note=Upon induction of apoptosis translocates together with BCL2L11 to mitochondria. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:8628263}. |
Top Pathways | Vasopressin-regulated water reabsorption |
DYNLL1 CRISPR/Cas9 KO Plasmid (h) - sc-416605 from Santa Cruz Biotechnology
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DYNLL1 HDR Plasmid (h) - sc-416605-HDR from Santa Cruz Biotechnology
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DYNLL1 Double Nickase Plasmid (h) - sc-416605-NIC from Santa Cruz Biotechnology
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DYNLL1 Double Nickase Plasmid (h2) - sc-416605-NIC-2 from Santa Cruz Biotechnology
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DYNLL1 CRISPR Activation Plasmid (h) - sc-416605-ACT from Santa Cruz Biotechnology
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DYNLL1 CRISPR Activation Plasmid (h2) - sc-416605-ACT-2 from Santa Cruz Biotechnology
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DYNLL1 Lentiviral Activation Particles (h) - sc-416605-LAC from Santa Cruz Biotechnology
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DYNLL1 Lentiviral Activation Particles (h2) - sc-416605-LAC-2 from Santa Cruz Biotechnology
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DYNLL1 siRNA (h) - sc-36228 from Santa Cruz Biotechnology
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DYNLL1 shRNA Plasmid (h) - sc-36228-SH from Santa Cruz Biotechnology
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DYNLL1 shRNA (h) Lentiviral Particles - sc-36228-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU147201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7588 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7588 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01892 from Sigma-Aldrich
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DYNLL1 siRNA (Human) - CRH5692 from Cohesion Biosciences
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DYNLL1 - MBS8229496 from MyBioSource
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DYNLL1 shRNA Plasmid (Human) - CHH5692 from Cohesion Biosciences
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