Gene Symbol | ST3GAL4 |
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Entrez Gene | 6484 |
Alt Symbol | CGS23, NANTA3, SAT3, SIAT4, SIAT4C, ST3GalIV, STZ |
Species | Human |
Gene Type | protein-coding |
Description | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
Other Description | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4|SAT-3|SIAT4-C|ST-4|ST3GalA.2|alpha 2,3-ST 4|alpha 2,3-sialyltransferase IV|alpha-3-N-acetylneuraminyltransferase|beta-galactoside alpha-2,3-sialyltransferase 4|gal-NAc6S|gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase|sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase)|sialyltransferase 4C (beta-galactoside alpha-2,3-sialytransferase) |
Swissprots | Q8NFG7 Q11206 O60497 A8K6B2 Q96QQ9 Q8N6A6 |
Accessions | CAS91691 EAW67693 EAW67694 EAW67695 EAW67696 EAW67697 Q11206 AB009393 AF035249 AAC14162 AF516602 AAM66431 AF516603 AAM66432 AF516604 AAM66433 AF525084 AAM81378 AK021929 BAB13940 AK128605 AK291577 BAF84266 AK314738 BAG37279 AL520639 AL529887 AY040826 AAK93790 BC010645 AAH10645 BI259855 BP320415 CR456858 CAG33139 DA210431 DA841563 EU831802 ACE87320 EU831879 ACE86638 L23767 AAA16460 X74570 CAA52662 XM_011542959 XP_011541261 XM_011542960 XP_011541262 XM_011542961 XP_011541263 XM_011542962 XP_011541264 NM_001254757 NP_001241686 NM_001254758 NP_001241687 NM_001254759 NP_001241688 NM_006278 NP_006269 |
Function | It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. Also acts on the corresponding 1,3- galactosyl derivative. {ECO:0000269|PubMed:8611500}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid. |
Tissue Specificity | Highly expressed in adult placenta, ovary and testes. |
Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |
ST3GAL4 / ST3Gal IV Antibody Blocking Peptide - LS-E16988 from LifeSpan Bioscience
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Recombinant Human ST3GAL4 Protein - H00006484-Q01 from Novus Biologicals
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ST3GAL4 Protein Lysate (APL10205) - APL10205 from Aviva Systems Biology
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ST3GAL4 Blocking Peptide - 33R-2869 from Fitzgerald
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ST3GAL4 Blocking Peptide - 33R-4030 from Fitzgerald
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ST3GAL4 - H00006484-Q01-10 from Acris Antibodies
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ST3GAL4 - H00006484-Q01-25 from Acris Antibodies
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ST3GAL4 fusion protein - ag17601 from Proteintech Group
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ST3GAL4 fusion protein - ag3665 from Proteintech Group
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Recombinant Human CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4(ST3GAL4) - CSB-YP612121HU CSB-EP612121HU CSB-BP612121HU CSB-MP612121HU from Cusabio
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ST3GAL4 Protein - NBP2-13390PEP from Novus Biologicals
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ST3GAL4-Blocking-Peptide-N-Term - BP22025a from Abgent, a WuXi AppTec company
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ST3GAL4 Peptide, Human - M34GP15236H from Creative Peptides
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ST3GAL4 Protein Lysate - orb333184 from Biorbyt
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CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4), Recombinant Protein - MBS1444909 from MyBioSource
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CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4), Recombinant Protein - MBS1171012 from MyBioSource
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