Gene Symbol | Ube2l6 |
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Entrez Gene | 56791 |
Alt Symbol | 2810489I21Rik, RIG-B, UBCH8, Ubce8, Ubcm8 |
Species | Mouse |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2L 6 |
Other Description | E2 ubiquitin conjugating enzyme|ubiquitin carrier protein L6|ubiquitin-conjugating enzyme 8|ubiquitin-protein ligase L6|ubiquitin/ISG15-conjugating enzyme E2 L6 |
Swissprots | Q922F1 Q3U8R0 Q9CQN0 Q9QZU9 |
Accessions | EDL27303 Q9QZU9 AF159230 AAD55978 AK010942 BAB27282 AK013452 BAB28861 AK152010 BAE30873 AK152066 AK152113 BAE30957 AK168695 BAE40539 AK171629 BAE42574 AK206200 AK212910 BC008238 AAH08238 CJ300190 CT010270 CAJ18478 NM_019949 NP_064333 |
Function | Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3 (By similarity). {ECO:0000250}. |
Top Pathways | Ubiquitin mediated proteolysis |
UBC8 CRISPR/Cas9 KO Plasmid (m) - sc-425306 from Santa Cruz Biotechnology
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UBC8 HDR Plasmid (m) - sc-425306-HDR from Santa Cruz Biotechnology
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UBC8 Double Nickase Plasmid (m) - sc-425306-NIC from Santa Cruz Biotechnology
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UBC8 Double Nickase Plasmid (m2) - sc-425306-NIC-2 from Santa Cruz Biotechnology
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UBC8 CRISPR Activation Plasmid (m) - sc-425306-ACT from Santa Cruz Biotechnology
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UBC8 CRISPR Activation Plasmid (m2) - sc-425306-ACT-2 from Santa Cruz Biotechnology
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UBC8 Lentiviral Activation Particles (m) - sc-425306-LAC from Santa Cruz Biotechnology
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UBC8 Lentiviral Activation Particles (m2) - sc-425306-LAC-2 from Santa Cruz Biotechnology
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UBC8 siRNA (m) - sc-41686 from Santa Cruz Biotechnology
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UBC8 shRNA Plasmid (m) - sc-41686-SH from Santa Cruz Biotechnology
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UBC8 shRNA (m) Lentiviral Particles - sc-41686-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN43816 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43816 from Sigma-Aldrich
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UBE2L6 siRNA (Mouse) - CRM5935 from Cohesion Biosciences
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UBE2L6 - MBS8206247 from MyBioSource
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shRNA set against Mouse UBE2L6 (NM_019949.2) - SHH439072 from Creative biogene
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Mouse UBE2L6 siRNA - orb285411 from Biorbyt
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UBE2L6 shRNA Plasmid (Mouse) - CHM5935 from Cohesion Biosciences
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