Gene Symbol | Mad2l1bp |
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Entrez Gene | 66591 |
Alt Symbol | 0610009D16Rik, 2510031P20Rik, AU018945, AW550977, C76045, CMT2A, CMT2B, Mad2lbp, mKIAA0110 |
Species | Mouse |
Gene Type | protein-coding |
Description | MAD2L1 binding protein |
Other Description | MAD2L1-binding protein |
Swissprots | Q9D0Y3 Q99J05 Q9DCX1 |
Accessions | EDL23474 Q9DCX1 AI851249 AK002377 BAB22054 AK004224 BAB23226 AK007974 AK011037 BAB27350 AK156569 BAE33758 AK220322 BAD90394 BC005768 AAH05768 NM_025649 NP_079925 |
Function | May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex. {ECO:0000250}. |
Subcellular Location | Nucleus, nucleoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle (By similarity). {ECO:0000250}. |
MAD2L1BP CRISPR/Cas9 KO Plasmid (m) - sc-426094 from Santa Cruz Biotechnology
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MAD2L1BP HDR Plasmid (m) - sc-426094-HDR from Santa Cruz Biotechnology
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MAD2L1BP Double Nickase Plasmid (m) - sc-426094-NIC from Santa Cruz Biotechnology
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MAD2L1BP Double Nickase Plasmid (m2) - sc-426094-NIC-2 from Santa Cruz Biotechnology
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MAD2L1BP CRISPR Activation Plasmid (m) - sc-426094-ACT from Santa Cruz Biotechnology
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MAD2L1BP CRISPR Activation Plasmid (m2) - sc-426094-ACT-2 from Santa Cruz Biotechnology
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MAD2L1BP Lentiviral Activation Particles (m) - sc-426094-LAC from Santa Cruz Biotechnology
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MAD2L1BP Lentiviral Activation Particles (m2) - sc-426094-LAC-2 from Santa Cruz Biotechnology
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MAD2L1BP siRNA (m) - sc-149212 from Santa Cruz Biotechnology
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MAD2L1BP shRNA Plasmid (m) - sc-149212-SH from Santa Cruz Biotechnology
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MAD2L1BP shRNA (m) Lentiviral Particles - sc-149212-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU007061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN35150 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35150 from Sigma-Aldrich
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MAD2L1BP siRNA (Mouse) - CRM6712 from Cohesion Biosciences
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shRNA set against Mouse MAD2 (NM_025649.3) - SHH336511 from Creative biogene
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Mouse MAD2L1BP siRNA - orb286188 from Biorbyt
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MAD2L1BP shRNA Plasmid (Mouse) - CHM6712 from Cohesion Biosciences
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